Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 2/20 | 0.52 |
| ▸ | MC3R | P41968 | 2/20 | 0.52 |
| ▸ | MC1R | Q01726 | 2/20 | 0.52 |
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.52 |
| ▸ | ABHD6 | Q9BV23 | 8/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908981 | 1.00 | SCD5 (0.57) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4629395 | 0.95 | HSD11B1 (0.61) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4964339 | 0.95 | HSD11B1 (0.61) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| Hydrochloric Acid SCHEMBL29238125 | 0.94 | HSD11B1 (0.60) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL18862951 | 0.90 | HSD11B1 (0.48) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL18862950 | 0.90 | HSD11B1 (0.48) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11378515 | 0.87 | ABCB1 (0.57) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL17092974 | 0.87 | SCD5 (0.45) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11377372 | 0.86 | SCD5 (0.54) | SCD5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4961994 | 0.84 | SLC18A2 (0.55) | HRH3MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685734-B2 | ATM kinase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20210188827-A1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. | 2021-06-24 | — | — | US | disclosed |
| WO-2021113506-A1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685734-B2 | ATM kinase inhibitors and compositions and methods of use thereof | ATM, CHEK2, CHEK1 | SCD5 3683/4885GABRA1 4227/4885GABRG2 3655/4885 |
| US-20210188827-A1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | ATM, CHEK2, CHEK1 | SCD5 3683/4885GABRA1 4227/4885GABRG2 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.