Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9103077 | 0.87 | GRM6 (0.38) | GRM6ARELANEADRA1AADRA1B | |
| SCHEMBL2711658 | 0.84 | ELANE (0.43) | ELANEADRA1AADRA1BTSHRCTNNB1 | |
| SCHEMBL4352323 | 0.81 | MEN1 (0.46) | GRM6ARMEN1ESR1KMT2A | |
| SCHEMBL2217741 | 0.79 | TRPA1 (0.45) | GRM6ARADRA1AADRA1BTSHR | |
| SCHEMBL6984283 | 0.79 | SLC7A5 (0.38) | GRM6ARELANEADRA1AADRA1B | |
| SCHEMBL25142572 | 0.78 | HSD17B10 (0.45) | GRM6ARADRA1AADRA1BTSHR | |
| SCHEMBL486746 | 0.78 | KMT2A (0.46) | GRM6ARADRA1AADRA1BTSHR | |
| SCHEMBL5080219 | 0.77 | TSHR (0.44) | GRM6ELANEADRA1AADRA1BTSHR | |
| SCHEMBL109178 | 0.76 | TSHR (0.50) | GRM6ELANEADRA1AADRA1BTSHR | |
| SCHEMBL30111657 | 0.76 | TSHR (0.50) | GRM6ELANEADRA1AADRA1BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440097-B1 | HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS | RODENSTOCK GMBH (DE) | 2008-03-12 | — | — | EP | claimed |
| US-6933325-B2 | High index curable photochromic composition and its process | RODENSTOCK GMBH (DE) | 2005-08-23 | — | — | US | claimed |
| EP-1440097-A2 | HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS | Rodenstock GmbH (DE) | 2004-07-28 | — | — | EP | claimed |
| US-20030158284-A1 | High index curable photochromic composition and its process | SECOND OPTICAL HOLDING GMBH (DE) | 2003-08-21 | — | — | US | claimed |
| US-6583196-B2 | Blend containing polyethylene glycol di(meth)acrylate | RODENSTOCK NORTH AMERICA, INC. | 2003-06-24 | — | — | US | claimed |
| WO-2003033558-A2 | HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS | RODENSTOCK GMBH (DE) | 2003-04-24 | — | — | WO | claimed |
| WO-2002051876-A1 | CURABLE CASTING COMPOSITIONS HAVING A HIGH REFRACTIVE INDEX AND HIGH IMPACT RESISTANCE | RODENSTOCK NORTH AMERICA, INC. (US) | 2002-07-04 | — | — | WO | claimed |
| US-6309585-B1 | Curable casting compositions having a high refractive index and high impact resistance | RODENSTOCK NORTH AMERICA, INC. | 2001-10-30 | — | — | US | claimed |
| US-20010018478-A1 | Curable casting compositons having a high refractive index and high impact resistance | OPTISCHE WERKE G. RODENSTOCK KG (DE) | 2001-08-30 | — | — | US | claimed |
| WO-2000064655-A1 | HIGH INDEX CURABLE CASTING COMPOSITIONS | 2C OPTICS, INC. (US) | 2000-11-02 | — | — | WO | claimed |
| EP-1440097-B1 | HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS | RODENSTOCK GMBH (DE) | 2008-03-12 | — | — | EP | disclosed |
| US-6933325-B2 | High index curable photochromic composition and its process | RODENSTOCK GMBH (DE) | 2005-08-23 | — | — | US | disclosed |
| EP-1440097-A2 | HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS | Rodenstock GmbH (DE) | 2004-07-28 | — | — | EP | disclosed |
| US-20030158284-A1 | High index curable photochromic composition and its process | SECOND OPTICAL HOLDING GMBH (DE) | 2003-08-21 | — | — | US | disclosed |
| US-6583196-B2 | Blend containing polyethylene glycol di(meth)acrylate | RODENSTOCK NORTH AMERICA, INC. | 2003-06-24 | — | — | US | disclosed |
| WO-2003033558-A2 | HIGH INDEX CURABLE PHOTOCHROMIC COMPOSITION AND ITS PROCESS | RODENSTOCK GMBH (DE) | 2003-04-24 | — | — | WO | disclosed |
| WO-2002051876-A1 | CURABLE CASTING COMPOSITIONS HAVING A HIGH REFRACTIVE INDEX AND HIGH IMPACT RESISTANCE | RODENSTOCK NORTH AMERICA, INC. (US) | 2002-07-04 | — | — | WO | disclosed |
| US-6309585-B1 | Curable casting compositions having a high refractive index and high impact resistance | RODENSTOCK NORTH AMERICA, INC. | 2001-10-30 | — | — | US | disclosed |
| US-20010018478-A1 | Curable casting compositons having a high refractive index and high impact resistance | OPTISCHE WERKE G. RODENSTOCK KG (DE) | 2001-08-30 | — | — | US | disclosed |
| WO-2000064655-A1 | HIGH INDEX CURABLE CASTING COMPOSITIONS | 2C OPTICS, INC. (US) | 2000-11-02 | — | — | WO | disclosed |