Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640412 | 0.75 | CYP1A2 (0.46) | CYP1A2MEN1KMT2ACNR2LMNA | |
| SCHEMBL27551457 | 0.73 | CYP1A2 (0.44) | CYP1A2MEN1KMT2ACNR2LMNA | |
| SCHEMBL10429897 | 0.72 | CYP1A2 (0.41) | CYP1A2MEN1KMT2ACNR2LMNA | |
| SCHEMBL7915728 | 0.70 | CYP1A2 (0.41) | CYP1A2MEN1KMT2ACNR2LMNA | |
| Cinnamonitrile SCHEMBL27780975 | 0.67 | ENPP2 (0.41) | CYP1A2MCL1KMT2ALMNAALDH1A1 | |
| Acrylonitrile SCHEMBL28262751 | 0.67 | CYP1A2 (0.44) | CYP1A2MCL1CNR2LMNAALDH1A1 | |
| SCHEMBL28745785 | 0.67 | CYP3A4 (0.38) | CYP1A2MEN1KMT2ACNR2LMNA | |
| Acrylonitrile SCHEMBL9422017 | 0.66 | CYP1A2 (0.46) | CYP1A2MCL1CNR2LMNAALDH1A1 | |
| Acrylonitrile SCHEMBL27987057 | 0.66 | LMNA (0.46) | CYP1A2KMT2ALMNAALDH1A1MAPT | |
| Acrylonitrile SCHEMBL28162413 | 0.66 | LMNA (0.46) | CYP1A2KMT2ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874711-A2 | ASYMMETRIC HYDROFORMYLATION PROCESS | Dow Gloval Technologies Inc. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007123957-A2 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2006116344-A2 | ASYMMETRIC HYDROFORMYLATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-11-02 | — | — | WO | disclosed |