SCHEMBL49629

SCHEMBL49629

c1ccc([N]c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
HTR3E A5X5Y0 2/20 0.45
HTR3B O95264 2/20 0.45
HTR3A P46098 2/20 0.45
HTR3D Q70Z44 2/20 0.45
HTR3C Q8WXA8 2/20 0.45
MIF P14174 1/20 0.45
SLC22A2 O15244 1/20 0.45
SLC22A1 O15245 1/20 0.45
SLC22A3 O75751 1/20 0.45
PLAU P00749 1/20 0.45
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NOS1 P29475 3/20 0.43
MAPT P10636 2/20 0.43
NOS3 P29474 2/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL3492611 0.96 ALDH1A1 (0.56) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL4392403 0.84 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AMAPTPKM
SCHEMBL11157503 0.82 MEN1 (0.71) ALDH1A1MEN1KMT2AMAPTRAB9A
SCHEMBL503321 0.82 ACHE (0.53) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL6573774 0.82 ALDH1A1 (0.43) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL9793669 0.82 MAPT (0.71) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL4396878 0.82 NFE2L2 (0.44) ALDH1A1MIFSLC22A2SLC22A1SLC22A3
SCHEMBL1118624 0.82 TSHR (0.53) ALDH1A1HTR3EHTR3BHTR3AHTR3D
SCHEMBL9186746 0.82 NOTUM (0.50) ALDH1A1MEN1KMT2AMAPTRAB9A
SCHEMBL1353413 0.79 ALDH1A1 (0.56) ALDH1A1MAPTTDP1CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27574 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324980-A Supported bifunctional polymer metalloporphyrin complex, preparation method and application 中国科学院长春应用化学研究所 2024-07-12 CN claimed
CN-118324788-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-07-12 CN claimed
CN-112789742-B Organic light emitting device 株式会社LG化学 2024-07-09 CN claimed
CN-118307568-A Light-emitting element and condensed polycyclic compound for use in the same 三星显示有限公司 2024-07-09 CN claimed
CN-118307574-A Boron-nitrogen compound and preparation method and application thereof 季华实验室 2024-07-09 CN claimed
CN-118290486-A Platinum complex based on periclamp carbene and derivative thereof, organic electroluminescent device and display device 浙江工业大学 2024-07-05 CN claimed
CN-115838336-B Spiro compound and application thereof 宁波卢米蓝新材料有限公司 2024-07-02 CN claimed
CN-118271349-A Organic compound, light-emitting element, and display panel 深圳市华星光电半导体显示技术有限公司 2024-07-02 CN claimed
CN-118284274-A Charge-transporting varnish 日产化学株式会社 2024-07-02 CN claimed
CN-118284640-A Triarylamine high molecular weight compound and organic electroluminescent element 保土谷化学工业株式会社 2024-07-02 CN claimed
US-4032643-A ANTILIPOLYTIC AGENTS, VASODILATION, ANTIBRADYKINETIC AGENTS ROUSSEL-UCLAF (FR) 1977-06-28 US claimed
US-4024128-A HYPOGLYCEMIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-05-17 US claimed
US-4021428-A 4-Piperidino-5-oxo-2-pyrazolines FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US claimed
US-3993630-A Polyimide, polyamide-imide or polyamide-acids with olefin end groups in combination with a reactive Schiff base compound CIBA-GEIGY CORPORATION (US) 1976-11-23 US claimed
US-3979350-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1976-09-07 US claimed
US-3966680-A Phenoxy-s-triazine chain coupler for polyesterification and novel polyesters MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-06-29 US claimed
US-3957726-A S-TRIAZINE-IMIDE COPOLYMERS CIBA-GEIGY CORPORATION (US) 1976-05-18 US claimed
US-3956339-A 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US claimed
US-3946011-A S-Triazine tetracarboxylic acids and dianhydrides CIBA-GEIGY CORPORATION (US) 1976-03-23 US claimed
US-3944525-A Crosslinked resins prepared from an N,N'-bis-imide and a schiff base CIBA-GEIGY CORPORATION (US) 1976-03-16 US claimed