Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940662 | 0.83 | ACLY (0.48) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15340969 | 0.78 | ACLY (0.39) | MAPTCYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9216534 | 0.78 | CYP4F2 (0.37) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3075311 | 0.76 | HSD17B10 (0.34) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9324197 | 0.76 | ACLY (0.48) | CYP1A2CYP2C9CYP2C19HSD17B10ALDH1A1 | |
| SCHEMBL601002 | 0.75 | ARG1 (0.52) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL600647 | 0.75 | ARG1 (0.52) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL600648 | 0.75 | ARG1 (0.52) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9256362 | 0.74 | CYP2D6 (0.43) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL232206 | 0.72 | KDM4E (0.36) | CYP1A2CYP2C9CYP2C19HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207897-A1 | 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[D] Azepines as 5-Ht2c Receptro Agonists | ELI LILLY AND COMPANY | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207897-A1 | 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[D] Azepines as 5-Ht2c Receptro Agonists | HTR2C, HTR2A, HTR1A | MAPT 4139/4885CYP1A2 181/4885CYP2D6 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.