Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712279 | 0.81 | GPR35 (0.57) | GPR35ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL2712274 | 0.81 | GPR35 (0.57) | GPR35ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL19210852 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMAPK1MAPT | |
| SCHEMBL29444506 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMAPK1MAPT | |
| SCHEMBL26984384 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2AHTTLMNAPKM | |
| SCHEMBL1821387 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2AHTTMAPTPKM | |
| SCHEMBL1906515 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2AHTTLMNAMAPK1 | |
| SCHEMBL496118 | 0.76 | GPR35 (0.54) | GPR35ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL496779 | 0.76 | GPR35 (0.54) | GPR35ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL14627171 | 0.75 | ALDH1A1 (0.42) | GPR35ALDH1A1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |