Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496118 | 1.00 | GPR35 (0.54) | GPR35ALDH1A1KMT2AHTTCA1 | |
| SCHEMBL6462163 | 0.90 | ALDH1A1 (0.52) | GPR35ALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL2712274 | 0.84 | GPR35 (0.57) | GPR35ALDH1A1KMT2AHTTCA1 | |
| SCHEMBL2712279 | 0.84 | GPR35 (0.57) | GPR35ALDH1A1KMT2AHTTCA1 | |
| SCHEMBL6459793 | 0.77 | ALDH1A1 (0.52) | GPR35ALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL496339 | 0.76 | GPR35 (0.51) | GPR35ALDH1A1KMT2AHTTKDM4E | |
| SCHEMBL16207437 | 0.76 | AKR1C3 (0.49) | GPR35ALDH1A1KMT2AHTTCA1 | |
| SCHEMBL1817535 | 0.76 | AKR1C3 (0.40) | ALDH1A1TTRMAPTTDP1 | |
| SCHEMBL1522094 | 0.75 | GPR35 (0.54) | GPR35ALDH1A1KMT2AHTTCA1 | |
| SCHEMBL10785960 | 0.74 | GPR35 (0.52) | GPR35ALDH1A1KMT2AHTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |