SCHEMBL4963428

SCHEMBL4963428

c1snnc1C1CN2CCC1CC2

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.44
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9342833 0.74 CHRNA7 (0.43) CHRNA7CHRM2CHRM4CHRM5CHRM1
SCHEMBL9343624 0.71 CHRNA7 (0.41) CHRNA7
SCHEMBL9342865 0.71 CHRNA7 (0.41) CHRNA7
SCHEMBL7820147 0.70 CHRNA7 (0.43) CHRNA7
SCHEMBL10433659 0.69 CHRNA7 (0.42) CHRNA7
Oxalic Acid SCHEMBL9342104 0.67 CHRNA7 (0.41) CHRNA7
SCHEMBL9293824 0.67
SCHEMBL9293655 0.67 CHRM2 (0.40) CHRNA7CHRM2CHRM1
SCHEMBL9458933 0.67 CHRNA7 (0.43) CHRNA7
SCHEMBL9486893 0.67 CHRNA7 (0.47) CHRNA7CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1532144-B1 QUINUCLIDINE DERIVATIVES AND THEIR USE NEUROSEARCH AS (DK) 2008-01-23 EP disclosed