SCHEMBL4963554

SCHEMBL4963554

COC(=O)C(Cc1ccc(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.46
PPARD Q03181 4/20 0.46
PPARA Q07869 3/20 0.46
LDHA P00338 2/20 0.46
LCK P06239 2/20 0.42
GAA P10253 1/20 0.41
XBP1 P17861 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM6B O15054 1/20 0.41
PTPRB P23467 1/20 0.41
ALOX15 P16050 2/20 0.40
HSD17B10 Q99714 2/20 0.40
NR1I2 O75469 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
CYP2C9 P11712 1/20 0.40
MIF P14174 1/20 0.40
TYR P14679 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5027133 0.88 LDHA (0.41) LDHALCKGAAXBP1ATM
SCHEMBL9845235 0.84 LCK (0.43) PPARGLCKGAAXBP1ATM
SCHEMBL4145724 0.82 ATM (0.43) LCKGAAXBP1ATMNPSR1
SCHEMBL10797920 0.81 ALOX15 (0.46) PPARGLCKGAAXBP1ATM
SCHEMBL8215159 0.81 FOLH1 (0.43) LCKKDM6BALOX15HSD17B10NR1I2
SCHEMBL30891619 0.80 KDM6B (0.45) LCKGAAXBP1ATMNPSR1
SCHEMBL9845237 0.80 KDM6B (0.45) PPARGLCKGAAXBP1ATM
SCHEMBL14856009 0.78 SLC7A5 (0.67) PPARGLCKNPSR1L3MBTL1ALOX15
SCHEMBL7892985 0.78 SLC7A5 (0.67) PPARGLCKNPSR1L3MBTL1ALOX15
SCHEMBL10656842 0.78 SLC7A5 (0.67) PPARGLCKNPSR1L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115044321-A Optical adhesive sheet 日东电工株式会社 2022-09-13 CN disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
EP-0184203-B1 VINYL BENZYL 2,2,6,6-TETRAMETHYL PIPERIDINES ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-15 EP disclosed
EP-0217149-B1 POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-01-30 EP disclosed
US-4957954-A TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
US-4885323-A POLYMER LIGHT STABILIZERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-12-05 US disclosed
US-4837257-A Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins ARGUS CHEMICAL CORPORATION (US) 1989-06-06 US disclosed
EP-0313676-A1 Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1989-05-03 EP disclosed
EP-0065655-B1 POLYMERIC LIGHT STABILIZERS HAVING AT LEAST ONE 2,2,6,6-TETRAALKYL PIPERIDYL GROUP AND SYNTHETIC RESIN COMPOSITIONS CONTAINING THE SAME ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-12-07 EP disclosed
EP-0260380-A2 Liquid polyvinyl chloride resin stabilizer systems based on complexes of organic triphosphites with zinc chloride Argus Chemical Corporation (US) 1988-03-23 EP disclosed
EP-0069871-A2 Copolymer light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1983-01-19 EP disclosed
EP-0068326-A2 Bis-phenol phosphates as clarifiers for polyolefin resins ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1983-01-05 EP disclosed
EP-0065655-A1 Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-12-01 EP disclosed
EP-0063180-A1 Beta-diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-10-27 EP disclosed
EP-0058434-A1 N-2-hydroxypropyl piperidines and process for preparing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1982-08-25 EP disclosed
EP-0047894-A2 Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins Argus Chemical Corporation (US) 1982-03-24 EP disclosed
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 EP disclosed
EP-0040286-A2 Polyvinyl halide resin compositions containing 1,3 Dicarbonyl compounds PHOENIX CHEMICAL CORPORATION (US) 1981-11-25 EP disclosed
US-4222931-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant ARGUS CHEMICAL CORPORATION (US) 1980-09-16 US disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 US disclosed