SCHEMBL496387

SCHEMBL496387

CCNC(=O)[C@@H]1CCCN1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.68
DPP7 Q9UHL4 1/20 0.51
TLR2 O60603 2/20 0.51
HTR2C P28335 5/20 0.50
HTR2B P41595 2/20 0.50
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TERT O14746 1/20 0.45
HTR2A P28223 1/20 0.44
GID4 Q8IVV7 1/20 0.42
DPP4 P27487 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL616732 1.00 PRCP (0.68) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL615383 1.00 PRCP (0.68) PRCPDPP7TLR2HTR2CHTR2B
Hydrochloric Acid SCHEMBL4320225 0.98 PRCP (0.66) PRCPDPP7TLR2HTR2CHTR2B
Acetic Acid SCHEMBL2183483 0.94 PRCP (0.62) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL13990631 0.94 PRCP (0.61) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL13359247 0.94 PRCP (0.61) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL4710537 0.94 PRCP (0.61) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL22019454 0.90 PRCP (0.57) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL23169303 0.90
Trifluoroacetic Acid SCHEMBL3332141 0.88 PRCP (0.56) PRCPDPP7TLR2HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343128-A Synthesis method of buserelin 成都君诚康正生物科技有限公司 2024-01-05 CN claimed
CN-116655745-B Application of intermediate in preparation of buserelin 杭州湃肽生化科技有限公司 2023-10-13 CN claimed
CN-116655745-A Application of intermediate in preparation of buserelin 杭州湃肽生化科技有限公司 2023-08-29 CN claimed
CN-109438560-B Liquid phase synthesis method of buserelin 江苏诺泰澳赛诺生物制药股份有限公司 2023-03-28 CN claimed
CN-110041407-B Method for synthesizing dessertraline acetate based on Fmoc dipeptide 南京肽业生物科技有限公司 2022-10-28 CN claimed
CN-108660131-B Preparation method of immobilized nitrile hydratase and (S) -N-ethylpyrrolidine-2-formamide 浙江工业大学 2020-07-21 CN claimed
WO-2008007930-A9 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD (KR) 2009-04-02 WO claimed
EP-1951746-A1 SOLUTION-PHASE SYNTHESIS OF LEUPROLIDE AND ITS INTERMEDIATES NANOKEM S.A. (UY) 2008-08-06 EP claimed
WO-2007059921-A1 SOLUTION-PHASE SYNTHESIS OF LEUPROLIDE AND ITS INTERMEDIATES NANOKEM S.A. (UY) 2007-05-31 WO claimed
US-20060217316-A1 Method for the treatment of prostate cancer GENIX THERAPEUTICS, INC. 2006-09-28 US claimed
WO-2004087190-A1 METHOD FOR THE TREATMENT OF PROSTATE CANCER GENIX THERAPEUTICS INC. (US) 2004-10-14 WO claimed
EP-1390055-A2 TRIPEPTIDE DERIVATIVES FOR THE TREATMENT OF POSTLESIONAL DISEASES OF THE NERVOUS SYSTEM Neurotell AG (CH) 2004-02-25 EP claimed
EP-1358204-A1 TRIPEPTIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Neurotell AG (CH) 2003-11-05 EP claimed
WO-2002062830-A1 TRIPEPTIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES NEUROTELL AG (CH) 2002-08-15 WO claimed
WO-2002062372-A2 TRIPEPTIDE DERIVATIVES FOR THE TREATMENT OF POSTLESIONAL DISEASES OF THE NERVOUS SYSTEM NEUROTELL AG (CH) 2002-08-15 WO claimed
US-5140009-A Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders TAP PHARMACEUTICALS, INC. (US) 1992-08-18 US claimed
US-4493828-A Use of thyrotropin releasing hormone and related peptides as poultry growth promotants MERCK & CO., INC. (US) 1985-01-15 US claimed
US-12116343-B2 Inhibitors of APOL1 and methods of using same VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-10-15 US disclosed
US-4493828-A Use of thyrotropin releasing hormone and related peptides as poultry growth promotants MERCK & CO., INC. (US) 1985-01-15 US disclosed
EP-0130409-A2 Slow-release composite and process for producing the same Takeda Chemical Industries, Ltd. (JP) 1985-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12116343-B2 Inhibitors of APOL1 and methods of using same APOL1, APOB, NPC1L1 PRCP 664/4885DPP7 516/4885TLR2 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.