SCHEMBL615383

SCHEMBL615383

CCNC(=O)C1CCCN1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.68
DPP7 Q9UHL4 1/20 0.51
TLR2 O60603 2/20 0.51
HTR2C P28335 5/20 0.50
HTR2B P41595 2/20 0.50
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TERT O14746 1/20 0.45
HTR2A P28223 1/20 0.44
GID4 Q8IVV7 1/20 0.42
DPP4 P27487 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL616732 1.00 PRCP (0.68) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL496387 1.00 PRCP (0.68) PRCPDPP7TLR2HTR2CHTR2B
Hydrochloric Acid SCHEMBL4320225 0.98 PRCP (0.66) PRCPDPP7TLR2HTR2CHTR2B
Acetic Acid SCHEMBL2183483 0.94 PRCP (0.62) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL13990631 0.94 PRCP (0.61) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL13359247 0.94 PRCP (0.61) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL4710537 0.94 PRCP (0.61) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL22019454 0.90 PRCP (0.57) PRCPDPP7TLR2HTR2CHTR2B
SCHEMBL23169303 0.90
Trifluoroacetic Acid SCHEMBL3332141 0.88 PRCP (0.56) PRCPDPP7TLR2HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108660131-B Preparation method of immobilized nitrile hydratase and (S) -N-ethylpyrrolidine-2-formamide 浙江工业大学 2020-07-21 CN claimed
CN-108660131-A The preparation method of immobilization hydrating nitrile group enzyme and (S)-N- ethyl pyrrolidine -2- formamides 浙江工业大学 2018-10-16 CN claimed
EP-1255752-A2 PYRROLE SUBSTITUTED 2-INDOLINONE PROTEIN KINASE INHIBITORS Sugen, Inc. (US) 2002-11-13 EP claimed
WO-2001060814-A2 PYRROLE SUBSTITUTED 2-INDOLINONE PROTEIN KINASE INHIBITORS SUGEN, INC. (US) 2001-08-23 WO claimed
US-5140009-A Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders TAP PHARMACEUTICALS, INC. (US) 1992-08-18 US claimed
CN-115703765-B Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof 上海赛默罗生物科技有限公司 2025-02-28 CN disclosed
US-11691995-B2 Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-07-04 US disclosed
US-20230101819-A1 SMYD Inhibitors EPIZYME INC (US) 2023-03-30 US disclosed
CN-115703765-A Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof 上海赛默罗生物科技有限公司 2023-02-17 CN disclosed
US-20210198252-A1 SMYD INHIBITORS EPIZYME INC (US) 2021-07-01 US disclosed
CN-108660131-B Preparation method of immobilized nitrile hydratase and (S) -N-ethylpyrrolidine-2-formamide 浙江工业大学 2020-07-21 CN disclosed
US-20190322660-A1 SMYD INHIBITORS Epizyme, Inc. 2019-10-24 US disclosed
EP-0144230-B1 GROWTH PROMOTANTS FOR ANIMALS Pfizer Limited (GB) 1990-08-08 EP disclosed
US-4758552-A Gonadoliberin derivatives containing an aromatic aminocarboxylic acid in the 6-position, pharmaceutical and veterinary compositions containing them and process for preparing same INNOFINANCE ALTALANOS INNOVACIOS PENZINTEZET (HU) 1988-07-19 US disclosed
US-4647553-A Gonadoliberin derivatives and process for the preparation thereof INNOVACIOS ALAP KOZPONTI VALTO ES HITELBANK RT. (HU) 1987-03-03 US disclosed
US-4562197-A CATTLE, POULTRY PFIZER INC. (US) 1985-12-31 US disclosed
US-4554100-A ENZYME INHIBITORS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1985-11-19 US disclosed
EP-0049628-B1 NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH, USEFUL AS LHRH ANTAGONISTS, METHODS OF MAKING THEM, AND THEIR PHARMACEUTICAL USES SYNTEX (U.S.A.) INC. (US) 1985-07-03 EP disclosed
EP-0144230-A2 Growth promotants for animals Pfizer Limited (GB) 1985-06-12 EP disclosed
EP-0130409-A2 Slow-release composite and process for producing the same Takeda Chemical Industries, Ltd. (JP) 1985-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691995-B2 Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications NOS2, NOS3, NOS1 PRCP 895/4885DPP7 1122/4885TLR2 2611/4885
US-20210198252-A1 SMYD INHIBITORS SMYD3, SMYD2, SMURF2 PRCP 3133/4885DPP7 4011/4885TLR2 4802/4885
US-20190322660-A1 SMYD INHIBITORS SMYD2, SMYD3, SMURF2 PRCP 3293/4885DPP7 4067/4885TLR2 4763/4885
US-20230101819-A1 SMYD Inhibitors SMYD3, SMYD2, SMURF2 PRCP 3073/4885DPP7 3960/4885TLR2 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.