Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20163626 | 0.79 | CHRM3 (0.32) | — | |
| SCHEMBL2498049 | 0.75 | MEN1 (0.31) | MEN1KMT2APOLB | |
| SCHEMBL2496526 | 0.73 | — | — | |
| SCHEMBL3910716 | 0.70 | HSD11B1 (0.44) | MEN1KMT2AHSD11B1ALDH1A1NPSR1 | |
| SCHEMBL1722705 | 0.70 | — | — | |
| SCHEMBL2725107 | 0.68 | TSHR (0.31) | ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL8879528 | 0.67 | — | — | |
| SCHEMBL14910753 | 0.66 | — | — | |
| SCHEMBL2873479 | 0.66 | LMNA (0.33) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL343056 | 0.66 | LMNA (0.33) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |