SCHEMBL4964024

SCHEMBL4964024

CC(C)(C)c1ccc([S+](c2ccccc2)c2ccccc2)cc1.O=C([O-])c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.50
CA1 P00915 2/20 0.50
RAB9A P51151 5/20 0.43
MAPT P10636 4/20 0.43
NPC1 O15118 3/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
XBP1 P17861 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SRD5A2 P31213 1/20 0.41
LMNA P02545 1/20 0.40
KCNK9 Q9NPC2 1/20 0.40
CA4 P22748 1/20 0.40
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106850 0.91 SRD5A2 (0.47) CA2RAB9AMAPTNPC1KMT2A
SCHEMBL4961628 0.87 CA2 (0.67) CA2CA1RAB9ANPC1KMT2A
SCHEMBL30596850 0.81 SRD5A2 (0.62) RAB9AMAPTNPC1SMN1; SMN2SRD5A2
SCHEMBL3693052 0.80 HSD11B1 (0.43) CA2CA1RAB9AMAPTNPC1
SCHEMBL4962446 0.79 CES2 (0.48) CA2CA1RAB9ANPC1SRD5A2
SCHEMBL6117135 0.78 SMN1; SMN2 (0.48) RAB9AMAPTNPC1KMT2AMEN1
SCHEMBL6117882 0.78 SMN1; SMN2 (0.48) RAB9AMAPTNPC1KMT2AMEN1
Terephthalic Acid SCHEMBL107592 0.78 CA2 (0.62) CA2CA1MAPTSMN1; SMN2CA4
Hydrochloric Acid SCHEMBL31425016 0.77 SMN1; SMN2 (0.47) RAB9AMAPTNPC1KMT2AMEN1
SCHEMBL107752 0.76 TSHR (0.44) RAB9AMAPTNPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP claimed
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed