Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908647 | 0.84 | ABCB11 (0.39) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL2906962 | 0.82 | ABCB11 (0.36) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL2908881 | 0.78 | CYP1A2 (0.40) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL6053569 | 0.78 | CYP1A2 (0.40) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL2937343 | 0.76 | CYP1A2 (0.36) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL2906181 | 0.75 | ABCB11 (0.40) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL2910744 | 0.74 | ABCB11 (0.40) | — | |
| SCHEMBL2906360 | 0.74 | SLC29A1 (0.36) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL4264484 | 0.74 | CYP1A2 (0.34) | LMNARAB9ACYP3A4PKMHPGD | |
| SCHEMBL3005625 | 0.73 | CYP1A2 (0.37) | LMNARAB9ACYP3A4PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-A4 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2008-03-05 | — | — | EP | disclosed |
| EP-1358198-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG Chem Investment, Ltd. (KR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002057288-A1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD. (KR) | 2002-07-25 | — | — | WO | disclosed |