Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 7/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.39 |
| ▸ | DAGLB | Q8NCG7 | 4/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965210 | 0.89 | DAGLA (0.40) | DAGLAABHD6DAGLB | |
| SCHEMBL4964653 | 0.86 | DRD4 (0.42) | DRD4LTA4HDAGLAABHD6DAGLB | |
| SCHEMBL4314108 | 0.84 | DRD4 (0.53) | DRD4ADAMTS5 | |
| SCHEMBL4965205 | 0.81 | DAGLA (0.41) | DAGLAABHD6DAGLB | |
| SCHEMBL4962995 | 0.75 | DAGLA (0.41) | DAGLAABHD6DAGLB | |
| SCHEMBL4311966 | 0.73 | CYP1A2 (0.46) | CYP19A1 | |
| SCHEMBL4306661 | 0.71 | CYP19A1 (0.48) | ADAMTS5RAB9ACYP19A1 | |
| SCHEMBL4308692 | 0.70 | DRD4 (0.52) | DRD4ADAMTS5 | |
| SCHEMBL11980678 | 0.68 | SCD5 (0.48) | DAGLAABHD6NPC1RAB9A | |
| SCHEMBL11470413 | 0.67 | HPGD (0.50) | LTA4HHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |