Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 13/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 7/20 | 0.41 |
| ▸ | DAGLB | Q8NCG7 | 6/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965210 | 0.84 | DAGLA (0.40) | DAGLAABHD6DAGLBHSD11B1 | |
| SCHEMBL4309159 | 0.83 | CYP2C9 (0.47) | — | |
| SCHEMBL4964327 | 0.81 | DRD4 (0.42) | DAGLAABHD6DAGLB | |
| SCHEMBL4312797 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL4312837 | 0.75 | CCR3 (0.42) | — | |
| SCHEMBL4310318 | 0.74 | AVPR2 (0.40) | — | |
| SCHEMBL13667365 | 0.74 | AVPR2 (0.40) | — | |
| SCHEMBL13667364 | 0.74 | AVPR2 (0.40) | — | |
| SCHEMBL4962541 | 0.73 | HRH3 (0.35) | — | |
| SCHEMBL4962995 | 0.72 | DAGLA (0.41) | DAGLAABHD6DAGLBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |