Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964697 | 0.85 | CNR1 (0.61) | EPHX2CNR1MEN1KMT2A | |
| SCHEMBL2950520 | 0.83 | EPHX2 (0.65) | EPHX2CNR1ALDH1A1LMNAMEN1 | |
| SCHEMBL7306841 | 0.83 | AKR1C3 (0.62) | EPHX2CNR1MEN1KMT2AHDAC3 | |
| SCHEMBL20789981 | 0.81 | TSHR (0.62) | ALDH1A1LMNANPC1NPSR1POLB | |
| SCHEMBL8564336 | 0.81 | MEN1 (0.83) | EPHX2CNR1ALDH1A1LMNAMEN1 | |
| SCHEMBL15916787 | 0.81 | NPC1 (0.64) | EPHX2ALDH1A1LMNANPC1NPSR1 | |
| SCHEMBL3977265 | 0.81 | MEN1 (0.64) | EPHX2CNR1MEN1KMT2AHDAC3 | |
| SCHEMBL14919477 | 0.80 | MEN1 (0.68) | EPHX2CNR1LMNAMEN1KMT2A | |
| SCHEMBL4274699 | 0.80 | CNR1 (0.88) | EPHX2CNR1MEN1KMT2A | |
| SCHEMBL2962589 | 0.80 | MEN1 (0.62) | EPHX2CNR1MEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517991-B2 | N-sulfonylpiperidine cannabinoid receptor 1 antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1814550-A2 | N-SULFONYLPIPERIDINE CANNABINOID RECEPTOR 1 ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006044362-A2 | N-SULFONYLPIPERIDINE CANNABINOID RECEPTOR 1 ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060079556-A1 | N-sulfonylpiperidine cannabinoid receptor 1 antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079556-A1 | N-sulfonylpiperidine cannabinoid receptor 1 antagonists | CNR1, CNR2, NPY1R | EPHX2 1348/4885CNR1 1/4885ALDH1A1 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.