Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974715 | 0.83 | EPHX2 (0.65) | EPHX2CNR1MEN1KMT2ATSHR | |
| SCHEMBL4964697 | 0.81 | CNR1 (0.61) | AKR1C3EPHX2CNR1MEN1KMT2A | |
| SCHEMBL6795564 | 0.80 | MEN1 (0.60) | EPHX2CNR1MEN1KMT2ATSHR | |
| SCHEMBL2950520 | 0.80 | EPHX2 (0.65) | EPHX2CNR1MEN1KMT2AHDAC3 | |
| SCHEMBL23497882 | 0.78 | KMT2A (0.61) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL29784786 | 0.78 | KMT2A (0.61) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL29784775 | 0.78 | KMT2A (0.61) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL24754404 | 0.78 | KMT2A (0.61) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL31684038 | 0.78 | KMT2A (0.61) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL4705021 | 0.77 | MEN1 (0.65) | AKR1C3EPHX2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |