Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23653038 | 0.69 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL31174789 | 0.68 | MGLL (0.35) | — | |
| SCHEMBL5048349 | 0.67 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL11366516 | 0.65 | GAA (0.42) | ALDH1A1 | |
| SCHEMBL25100331 | 0.65 | POLB (0.41) | ALDH1A1 | |
| SCHEMBL22484754 | 0.65 | POLB (0.41) | ALDH1A1 | |
| SCHEMBL11449432 | 0.64 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL11467166 | 0.64 | GAA (0.40) | ALDH1A1 | |
| SCHEMBL11109281 | 0.63 | MAPK1 (0.32) | — | |
| SCHEMBL21863412 | 0.62 | MGLL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885357-A1 | BICYCLIC 6-ALKYLIDENE-PENEMS AS CLASS-D BETA-LACTAMASES INHIBITORS | Wyeth (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006130588-A1 | BICYCLIC 6-ALKYLIDENE-PENEMS AS CLASS-D BETA-LACTAMASES INHIBITORS | WYETH (US) | 2006-12-07 | — | — | WO | disclosed |