SCHEMBL11467166

SCHEMBL11467166

CC1CCCc2nc3c(c(=O)n21)CCCC3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 5/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 3/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
HRH4 Q9H3N8 1/20 0.35
CYP2C9 P11712 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
KDM5B Q9UGL1 2/20 0.34
MAPT P10636 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C19 P33261 2/20 0.34
KDM5A P29375 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
USP2 O75604 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11449432 0.97 ALDH1A1 (0.40) GAAALDH1A1KDM4EHSD17B10HPGD
Benzene SCHEMBL11052377 0.71 FPR1 (0.30) HSD17B10
SCHEMBL11366516 0.70 GAA (0.42) GAAALDH1A1KDM4EHSD17B10HPGD
SCHEMBL2211807 0.69 ERCC1 (0.33) ALDH1A1POLB
SCHEMBL11049965 0.68 SMN1; SMN2 (0.53) GAAALDH1A1KDM4EHSD17B10HPGD
SCHEMBL11109281 0.68 MAPK1 (0.32) MAPK1
SCHEMBL11104503 0.68 NUAK1 (0.35) CYP2C9MAPTCYP1A2CYP3A4CYP2C19
Hydrochloric Acid SCHEMBL9741206 0.67 HTR1A (0.34) GAAALDH1A1HPGDCYP2C19SMN1; SMN2
SCHEMBL10860457 0.67 ALDH1A1 (0.54) GAAALDH1A1KDM4EHSD17B10HPGD
SCHEMBL11449986 0.67 GAA (0.54) GAAALDH1A1KDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4220771-A MORPHINE POTENTIATORS CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1980-09-02 US disclosed