SCHEMBL4965091

SCHEMBL4965091

c1ccc(COC2CCCCC2)c(COC2CCCCC2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CARM1 Q86X55 7/20 0.41
PRMT6 Q96LA8 5/20 0.41
PRMT1 Q99873 2/20 0.39
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
HTR7 P34969 1/20 0.38
HTR2B P41595 1/20 0.38
HTR3A P46098 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HTR4 Q13639 1/20 0.38
PRMT5 O14744 1/20 0.37
WDR77 Q9BQA1 1/20 0.37
DCPS Q96C86 1/20 0.37
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
CTSK P43235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12920703 0.91 KDM4E (0.41) KDM4EL3MBTL1CARM1PRMT6PRMT1
SCHEMBL14394440 0.88 KDM4E (0.42) KDM4EL3MBTL1CARM1PRMT6PRMT1
SCHEMBL31381336 0.87 CARM1 (0.56) KDM4EL3MBTL1CARM1PRMT6HTR2A
SCHEMBL1836246 0.87 KDM4E (0.51) KDM4EL3MBTL1LMNA
SCHEMBL13806992 0.87 EPHX2 (0.47) KDM4EL3MBTL1CARM1PRMT6HTR2A
SCHEMBL1837026 0.87 KDM4E (0.51) KDM4EL3MBTL1LMNA
SCHEMBL4920251 0.87 CARM1 (0.56) KDM4EL3MBTL1CARM1PRMT6
SCHEMBL1837906 0.87 KDM4E (0.51) KDM4EL3MBTL1LMNA
SCHEMBL4965765 0.86 KDM4E (0.43) KDM4EL3MBTL1CARM1PRMT6PRMT1
SCHEMBL943043 0.85 APOBEC3G (0.41) KDM4EL3MBTL1CARM1PRMT6PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed
US-6924323-B2 Sulfonium salt compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B KDM4E 1259/4885L3MBTL1 3356/4885CARM1 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.