SCHEMBL4965765

SCHEMBL4965765

c1cc(COC2CCCCC2)c(COC2CCCCC2)c(COC2CCCCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
DCPS Q96C86 1/20 0.40
CARM1 Q86X55 6/20 0.35
PRMT6 Q96LA8 5/20 0.35
QRFPR Q96P65 1/20 0.34
GLA P06280 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SCN9A Q15858 1/20 0.33
PRMT1 Q99873 1/20 0.33
NPC1 O15118 1/20 0.33
EPHX1 P07099 1/20 0.33
SLC6A1 P30531 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1838443 0.88 KDM4E (0.48) KDM4EL3MBTL1DCPSQRFPRNPSR1
SCHEMBL1833410 0.88 KDM4E (0.48) KDM4EL3MBTL1DCPSQRFPRNPSR1
SCHEMBL1841324 0.88 KDM4E (0.48) KDM4EL3MBTL1DCPSQRFPRNPSR1
SCHEMBL1837187 0.86 KDM4E (0.49) KDM4EL3MBTL1DCPSCARM1PRMT6
SCHEMBL4965091 0.86 KDM4E (0.46) KDM4EL3MBTL1DCPSCARM1PRMT6
SCHEMBL1837953 0.79 KDM4E (0.52) KDM4EL3MBTL1QRFPRSCN9ANPC1
SCHEMBL1836426 0.79 KDM4E (0.52) KDM4EL3MBTL1QRFPRSCN9ANPC1
SCHEMBL1838623 0.79 KDM4E (0.52) KDM4EL3MBTL1QRFPRSCN9ANPC1
SCHEMBL1837026 0.78 KDM4E (0.51) KDM4EL3MBTL1NPSR1
SCHEMBL13806992 0.78 EPHX2 (0.47) KDM4EL3MBTL1CARM1PRMT6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314725-B1 SULFONIUM SALT COMPOUND WAKO PURE CHEM IND LTD (JP) 2008-03-19 EP disclosed
US-6924323-B2 Sulfonium salt compound WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
US-20040033434-A1 Sulfonium salt compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2004-02-19 US disclosed
EP-1314725-A1 SULFONIUM SALT COMPOUND Wako Pure Chemical Industries, Ltd. (JP) 2003-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040033434-A1 Sulfonium salt compound SPIN1, RER1, SPIN2B KDM4E 1259/4885L3MBTL1 3356/4885DCPS 3755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.