Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19266046 | 0.89 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL9230930 | 0.84 | ALDH1A1 (0.34) | ALDH1A1TSHRPOLB | |
| SCHEMBL7118252 | 0.83 | CHRM2 (0.31) | ALDH1A1TSHRPOLB | |
| SCHEMBL5358470 | 0.81 | — | — | |
| SCHEMBL614377 | 0.81 | TSHR (0.48) | ALDH1A1TSHRPOLB | |
| SCHEMBL11338133 | 0.78 | HTT (0.30) | — | |
| SCHEMBL8252306 | 0.77 | CHRM2 (0.33) | ALDH1A1POLB | |
| SCHEMBL9230926 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TSHRPOLB | |
| SCHEMBL24387394 | 0.76 | ALOX15 (0.36) | ALDH1A1POLB | |
| SCHEMBL9245957 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630116-B1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | SIRRUS INC (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-3208287-A1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | Sirrus, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| US-8884051-B2 | Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent | BIOFORMIX INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-8884051-B2 | Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent | BIOFORMIX INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130281580-A1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | BIOFORMIX INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281580-A1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | BIOFORMIX INC. (US) | 2013-10-24 | — | — | US | disclosed |
| WO-2012054633-A2 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | BIOFORMIX, LLC (US) | 2012-04-26 | — | — | WO | disclosed |