Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Diaminopurine SCHEMBL2316818 | 0.75 | KDM4E (0.32) | NUDT1 | |
| 6-Chloroguanine SCHEMBL3268234 | 0.72 | MMP12 (0.33) | NUDT1 | |
| SCHEMBL3269477 | 0.68 | L3MBTL1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7207981 | 0.68 | — | — | |
| SCHEMBL3269217 | 0.64 | ADORA2A (0.35) | — | |
| SCHEMBL3273300 | 0.64 | CCR1 (0.42) | — | |
| SCHEMBL3269209 | 0.63 | HPGDS (0.38) | — | |
| SCHEMBL3268785 | 0.63 | KDM4E (0.38) | — | |
| SCHEMBL3275293 | 0.63 | CYP3A4 (0.40) | — | |
| SCHEMBL3273070 | 0.62 | CDK5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4054057-B2 | — | — | 2008-02-27 | — | — | JP | claimed |
| EP-0702683-B1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2003-09-17 | — | — | EP | claimed |