Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965638 | 0.85 | OPRM1 (0.41) | OPRM1OPRK1OPRD1SLC2A1 | |
| SCHEMBL4965646 | 0.85 | OPRM1 (0.41) | OPRM1OPRK1OPRD1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL4965277 | 0.84 | OPRM1 (0.41) | OPRM1OPRK1OPRD1KMT2ARAB9A | |
| SCHEMBL4965138 | 0.84 | MCHR1 (0.43) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL4963457 | 0.84 | SLC2A1 (0.42) | OPRM1OPRK1OPRD1SLC2A1 | |
| SCHEMBL4965826 | 0.84 | OPRM1 (0.57) | OPRM1OPRK1OPRD1KMT2ARAB9A | |
| SCHEMBL4966598 | 0.84 | MCHR1 (0.41) | OPRM1OPRK1OPRD1KMT2ARAB9A | |
| SCHEMBL4966629 | 0.84 | SLC2A1 (0.37) | OPRM1OPRK1OPRD1KMT2ARAB9A | |
| SCHEMBL4966256 | 0.84 | AURKA (0.35) | KMT2ARAB9AMEN1NPC1POLB | |
| SCHEMBL4971525 | 0.83 | OPRM1 (0.40) | OPRM1OPRK1KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730140-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-06-25 | — | — | EP | claimed |