Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967478 | 0.90 | KDM4E (0.49) | MCHR1SLC2A1KDM4EMEN1KMT2A | |
| SCHEMBL4965638 | 0.89 | OPRM1 (0.41) | SLC2A1SMN1; SMN2LMNAHDAC3HDAC1 | |
| SCHEMBL4963457 | 0.88 | SLC2A1 (0.42) | SLC2A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL4966629 | 0.87 | SLC2A1 (0.37) | SLC2A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL4968057 | 0.85 | OPRM1 (0.44) | MCHR1KDM4ERAB9AHPGDALDH1A1 | |
| SCHEMBL4965633 | 0.85 | OPRM1 (0.45) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL4965646 | 0.84 | OPRM1 (0.41) | SLC2A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4965252 | 0.84 | OPRM1 (0.41) | MCHR1SLC2A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4965277 | 0.84 | OPRM1 (0.41) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4966256 | 0.83 | AURKA (0.35) | MCHR1SLC2A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730140-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-06-25 | — | — | EP | claimed |