Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15559211 | 0.70 | KDM4E (0.32) | KMT2AKDM4EMEN1MAPTCYP2C9 | |
| SCHEMBL1607925 | 0.66 | SRD5A2 (0.39) | KMT2AKDM4EMAPT | |
| SCHEMBL5599182 | 0.63 | KDM4E (0.44) | KMT2AKDM4EMEN1MAPTPTGDR2 | |
| SCHEMBL161226 | 0.61 | KDM4E (0.50) | KMT2AKDM4EMEN1MAPTPTGDR2 | |
| SCHEMBL29839614 | 0.61 | HSP90AA1 (0.34) | — | |
| SCHEMBL6921914 | 0.61 | KDM4E (0.43) | KMT2AKDM4EMEN1MAPTPTGDR2 | |
| SCHEMBL4359674 | 0.60 | KDM4E (0.45) | KMT2AKDM4EMEN1MAPT | |
| SCHEMBL29339016 | 0.60 | KMT2A (0.35) | KMT2AKDM4EMEN1 | |
| SCHEMBL15558595 | 0.60 | RBP4 (0.33) | — | |
| SCHEMBL307050 | 0.60 | KDM4E (0.53) | KMT2AKDM4EMEN1MAPTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896454-A1 | AMlNO-5-(5-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR -SECRETASE MODULATION | Wyeth a Corporation of the State of Delaware (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007005366-A1 | AMlNO-5-(5-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR β-SECRETASE MODULATION | WYETH (US) | 2007-01-11 | — | — | WO | claimed |