SCHEMBL4965655

CC(C)(C)c1ccc(OP(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1.CCCCCCCCCCCCCOP(O)O

nearest known ligand 0.40

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	THRA	P10827	1/20	0.40

▸	THRB	P10828	1/20	0.40

▸	ESR1	P03372	2/20	0.37

▸	GHSR	Q92847	1/20	0.34

▸	KDM4E	B2RXH2	2/20	0.33

▸	GAA	P10253	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	RECQL	P46063	1/20	0.33

▸	S1PR1	P21453	1/20	0.32

▸	VDR	P11473	1/20	0.32

▸	CNR1	P21554	1/20	0.32

▸	CNR2	P34972	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL466235	0.90	THRA (0.40)	THRATHRBESR1GHSRKDM4E
SCHEMBL11213999	0.90	THRA (0.40)	THRATHRBESR1GHSRKDM4E
SCHEMBL2183919	0.90	THRA (0.40)	THRATHRBESR1GHSRKDM4E
SCHEMBL6905040	0.90	THRA (0.40)	THRATHRBESR1GHSRKDM4E
SCHEMBL97771	0.90	THRA (0.40)	THRATHRBESR1GHSRKDM4E
SCHEMBL7948647	0.88	THRA (0.41)	THRATHRBESR1GHSRKDM4E
SCHEMBL7951307	0.88	THRA (0.41)	THRATHRBESR1GHSRKDM4E
SCHEMBL2710797	0.88	THRA (0.41)	THRATHRBESR1GHSRKDM4E
SCHEMBL7954050	0.88	THRA (0.41)	THRATHRBESR1GHSRKDM4E
SCHEMBL19026571	0.88	THRA (0.41)	THRATHRBESR1GHSRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1489140-B1	FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN COMPOSITION	TEIJIN CHEMICALS LTD (JP)	2008-08-13	—	—	EP	disclosed