SCHEMBL466235

SCHEMBL466235

CCCCCCCCOP(Oc1ccc(C(C)(C)C)cc1C(C)(C)C)Oc1ccc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
ESR1 P03372 2/20 0.37
GHSR Q92847 1/20 0.36
KDM4E B2RXH2 3/20 0.35
RECQL P46063 1/20 0.35
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
VDR P11473 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905040 1.00 THRA (0.40) THRATHRBESR1GHSRKDM4E
SCHEMBL97771 1.00 THRA (0.40) THRATHRBESR1GHSRKDM4E
SCHEMBL2183919 0.97 THRA (0.40) THRATHRBESR1GHSRKDM4E
SCHEMBL11213999 0.97 THRA (0.40) THRATHRBESR1GHSRKDM4E
SCHEMBL9240797 0.92 KDM4E (0.35) THRATHRBESR1GHSRKDM4E
SCHEMBL11265850 0.92 THRA (0.36) THRATHRBESR1GHSRSMN1; SMN2
SCHEMBL12486318 0.91 ESR1 (0.37) THRATHRBESR1GHSRKDM4E
SCHEMBL12485303 0.91 ESR1 (0.37) THRATHRBESR1GHSRKDM4E
SCHEMBL10604029 0.91 THRA (0.35) THRATHRBESR1GHSRKDM4E
SCHEMBL4965655 0.90 THRA (0.40) THRATHRBESR1GHSRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220282064-A1 STABILIZER COMPOSITION BASF SE (DE) 2022-09-08 US claimed
EP-4004099-A1 STABILIZER COMPOSITION BASF SE (DE) 2022-06-01 EP claimed
US-10934423-B2 Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers BASF SE (DE) 2021-03-02 US claimed
WO-2021021871-A1 STABILIZER COMPOSITION BASF SE (DE) 2021-02-04 WO claimed
US-20200385570-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-12-10 US claimed
EP-3710145-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2020-09-23 EP claimed
EP-3649139-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND ORGANOPHOSPHORUS STABILIZERS BASF SE (DE) 2020-05-13 EP claimed
WO-2019010166-A1 STABILIZED POLYOLEFIN COMPOSITIONS COMPRISING BENZOFURANONES AND ORGANOPHOSPHORUS STABILIZERS BASF SE (DE) 2019-01-10 WO claimed
US-20190010307-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Organophosphorus Stabilizers BASF CORPORATION 2019-01-10 US claimed
US-7291662-B2 Nonylcyclohexylphosphite ester polyolefin stabilizers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-06 US claimed
US-20050222308-A1 Nonylcyclohexylphosphite ester polyolefin stabilizers CIBA SPECIALTY CHEMICALS CORP. 2005-10-06 US claimed
EP-3841166-B2 STABILIZED ROTOMOLDED POLYOLEFIN BASF SE (DE) 2025-05-07 EP disclosed
US-20240352229-A1 FLAME RETARDANT POLYOLEFIN ARTICLES BASF SE (DE) 2024-10-24 US disclosed
US-20240294750-A1 POLYCARBONATE COMPOSITIONS BASF SE (DE) 2024-09-05 US disclosed
US-12012542-B2 Flame retardant rotomolded polyolefin BASF SE (DE) 2024-06-18 US disclosed
EP-0926189-A2 A macromolecular material composition and a modifier for macromolecular material HITACHI CHEMICAL CO., LTD. (JP) 1999-06-30 EP disclosed
US-5833878-A DISPLAY COMPRISING POLYNORBORNANE RESIN FILMS; SHARPNESS JSR CORPORATION (JP) 1998-11-10 US disclosed
US-5298598-A Preparation of polyamide with mixture of phosphorus catalysts INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1994-03-29 US disclosed
US-5298594-A Charging caprolactam, water and alkali metal hypophosphite catalyst, purging air, heating to form prepolymer, charging prepolymer with cocatalyst, heating by raising temperature CHINESE PETROCHEMICAL DEVELOPMENT CORP. (TW) 1994-03-29 US disclosed
US-5290747-A Nylon 6 catalyst system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1994-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190010307-A1 Stabilized Polyolefin Compositions Comprising Benzofuranones and Organophosphorus Stabilizers PUF60, MORF4L1, BRPF1 THRA 3892/4885THRB 3884/4885ESR1 3393/4885
US-10934423-B2 Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers PUF60, MORF4L1, BRPF1 THRA 3892/4885THRB 3884/4885ESR1 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.