Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97771 | 1.00 | THRA (0.40) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL466235 | 1.00 | THRA (0.40) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL2183919 | 0.97 | THRA (0.40) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL11213999 | 0.97 | THRA (0.40) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL9240797 | 0.92 | KDM4E (0.35) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL11265850 | 0.92 | THRA (0.36) | THRATHRBESR1GHSRSMN1; SMN2 | |
| SCHEMBL12486318 | 0.91 | ESR1 (0.37) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL12485303 | 0.91 | ESR1 (0.37) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL10604029 | 0.91 | THRA (0.35) | THRATHRBESR1GHSRKDM4E | |
| SCHEMBL4965655 | 0.90 | THRA (0.40) | THRATHRBESR1GHSRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926189-B1 | A macromolecular material composition and a modifier for macromolecular material | HITACHI CHEMICAL CO LTD (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-0926189-A2 | A macromolecular material composition and a modifier for macromolecular material | HITACHI CHEMICAL CO., LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |