SCHEMBL4965677

SCHEMBL4965677

O=C(OCOc1ccccc1)OCOc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
MTNR1A P48039 4/20 0.48
MTNR1B P49286 4/20 0.48
PKM P14618 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
THRB P10828 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ALDH1A1 P00352 3/20 0.46
RECQL P46063 1/20 0.46
KCNA3 P22001 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TSHR P16473 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
PARP10 Q53GL7 1/20 0.46
ALPL P05186 1/20 0.44
ALPI P09923 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075116 0.90 TDP1 (0.53) ALOX15MTNR1AMTNR1BL3MBTL1ALDH1A1
SCHEMBL14370917 0.90 ALOX15 (0.50) ALOX15MTNR1AMTNR1BPKML3MBTL1
SCHEMBL10075124 0.88 MTNR1A (0.53) ALOX15MTNR1AMTNR1BL3MBTL1RECQL
SCHEMBL10075117 0.87 LMNA (0.51) ALOX15MTNR1AMTNR1BPKML3MBTL1
SCHEMBL29140273 0.86 ALOX15 (0.56) ALOX15MTNR1AMTNR1BPKML3MBTL1
Benzene SCHEMBL7593686 0.86 ALOX15 (0.56) ALOX15MTNR1AMTNR1BPKML3MBTL1
SCHEMBL2754113 0.86 CYP3A4 (0.50) ALOX15MTNR1AMTNR1BPKML3MBTL1
SCHEMBL4570321 0.84 ALOX15 (0.54) ALOX15MTNR1AMTNR1BPKML3MBTL1
SCHEMBL10075121 0.83 ALOX15 (0.44) ALOX15MTNR1AMTNR1BPKML3MBTL1
SCHEMBL10075120 0.83 MAPT (0.50) ALOX15MTNR1AMTNR1BPKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008034265-A1 PROCESS FOR THE PREPARATION OF ALKYLENE CARBONATES MCGILL UNIVERSITY (CA) 2008-03-27 WO disclosed