Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479553 | 1.00 | UMPS (0.45) | UMPSSLC5A2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4968792 | 0.88 | PYGL (0.51) | SLC5A2PYGL | |
| SCHEMBL6788896 | 0.83 | MAPK1 (0.44) | SLC5A2KDM4E | |
| SCHEMBL6789670 | 0.83 | MAPK1 (0.44) | SLC5A2KDM4E | |
| SCHEMBL6785286 | 0.83 | MAPK1 (0.44) | SLC5A2KDM4E | |
| SCHEMBL12693897 | 0.80 | UMPS (0.44) | UMPSSLC5A2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL12691584 | 0.80 | UMPS (0.44) | UMPSSLC5A2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4270606 | 0.80 | UMPS (0.44) | UMPSSLC5A2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6931518 | 0.80 | UMPS (0.44) | UMPSSLC5A2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13514156 | 0.80 | UMPS (0.44) | UMPSSLC5A2SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957086-A2 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007061798-A2 | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-05-31 | — | — | WO | disclosed |