SCHEMBL4968792

SCHEMBL4968792

O=C(O)c1ccc(C2OC(CO)C(O)C2O)nc1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PYGL P06737 7/20 0.51
SLC5A2 P31639 5/20 0.44
P4HA1 P13674 1/20 0.44
P4HTM Q9NXG6 1/20 0.44
LDHA P00338 1/20 0.42
HK1 P19367 1/20 0.41
HK2 P52789 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4965716 0.88 UMPS (0.45) PYGLSLC5A2
SCHEMBL17479553 0.88 UMPS (0.45) PYGLSLC5A2
SCHEMBL6789670 0.84 MAPK1 (0.44) SLC5A2
SCHEMBL6785286 0.84 MAPK1 (0.44) SLC5A2
SCHEMBL6788896 0.84 MAPK1 (0.44) SLC5A2
SCHEMBL6788640 0.78 PYGL (0.45) PYGLSLC5A2
SCHEMBL6789106 0.78 SLC5A2 (0.47) PYGLSLC5A2
SCHEMBL6788644 0.78 PYGL (0.45) PYGLSLC5A2
SCHEMBL6785076 0.78 PYGL (0.45) PYGLSLC5A2
SCHEMBL6785069 0.78 PYGL (0.45) PYGLSLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957086-A2 NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE CORNELL RESEARCH FOUNDATION, INC. (US) 2008-08-20 EP disclosed
WO-2007061798-A2 NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE CORNELL RESEARCH FOUNDATION, INC. (US) 2007-05-31 WO disclosed