Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935806 | 0.84 | SLC5A1 (0.49) | PDE4ATP53ALOX12NPSR1ELANE | |
| SCHEMBL1078509 | 0.81 | TP53 (0.58) | PDE4ATP53ALOX12PDE4BPDE4C | |
| SCHEMBL21621707 | 0.78 | ALDH1A1 (0.50) | TP53ALOX12NPSR1ELANECYP1A2 | |
| SCHEMBL1077879 | 0.76 | HPGD (0.50) | PDE4ATP53ALOX12NPSR1ELANE | |
| SCHEMBL3604654 | 0.74 | GLA (0.45) | NPSR1ELANECYP1A2NPC1RAB9A | |
| SCHEMBL18355727 | 0.74 | ALDH1A1 (0.51) | TP53ALOX12ELANECYP1A2NPC1 | |
| SCHEMBL18355722 | 0.74 | ALDH1A1 (0.60) | TP53ALOX12ELANEMAPK1MEN1 | |
| SCHEMBL4958802 | 0.72 | ALDH1A1 (0.57) | TP53ALOX12NPSR1ELANEPDE4D | |
| SCHEMBL16935867 | 0.72 | ALDH1A1 (0.54) | PDE4ATP53ALOX12NPSR1ELANE | |
| SCHEMBL18356070 | 0.72 | ELANE (0.50) | TP53ALOX12ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874734-A1 | 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS | Solvay Pharmaceuticals B.V. (NL) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006087355-A1 | 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2006-08-24 | — | — | WO | disclosed |