Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809748 | 0.89 | GAA (0.58) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL664857 | 0.87 | ALDH1A1 (0.65) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| Benzene SCHEMBL9407299 | 0.87 | ALDH1A1 (0.65) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL2877979 | 0.85 | ALDH1A1 (0.63) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL15650026 | 0.84 | L3MBTL1 (0.49) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL4675 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| Benzene SCHEMBL28096336 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL1870609 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| SCHEMBL3682233 | 0.82 | TSHR (0.56) | TSHRALDH1A1L3MBTL1MAPK1PAM | |
| Methyl Alcohol SCHEMBL3396251 | 0.81 | ALDH1A1 (0.61) | TSHRALDH1A1L3MBTL1MAPK1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835506-B2 | Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate | OCERA THERAPEUTICS, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-20180221320-A1 | TREATMENT AND PREVENTION OF MUSCLE LOSS USING L-ORNITHINE IN COMBINATION WITH AT LEAST ONE OF PHENYLACETATE AND PHENYLBUTYRATE | OCERA THERAPEUTICS LLC | 2018-08-09 | — | — | US | disclosed |
| WO-2017031131-A1 | TREATMENT AND PREVENTION OF MUSCLE LOSS USING L-ORNITHINE IN COMBINATION WITH AT LEAST ONE OF PHENYLACETATE AND PHENYLBUTYRATE | OCERA THERAPEUTICS, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| CN-103446716-B | Golf | DUNLOP SPORTS CO., LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-103313838-B | Method for producing long polymer film, lambda/4 plate, polarizing plate, and liquid crystal display device | KONICA MINOLTA,INC. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-104254791-A | METHOD FOR PRODUCING POLARIZING PLATE | KONICA MINOLTA INC | 2014-12-31 | — | — | CN | disclosed |
| CN-103446716-A | Golf ball | DUNLOP SPORTS CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-103304441-A | O-methoxyphenylacetic acid Schiff base and synthetic method and application thereof | UNIV NANJING NORMAL | 2013-09-18 | — | — | CN | disclosed |
| CN-103313838-A | Method for producing long polymer film, lambda/4 plate, polarizing plate, and liquid crystal display device | KONICA MINOLTA OPTO INC | 2013-09-18 | — | — | CN | disclosed |
| CN-101133018-A | Glycine transport inhibitors | GLAXO GROUP LTD (GB) | 2008-02-27 | — | — | CN | disclosed |
| EP-1888544-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006066109-A2 | HYDROXYSTEROID DEHYDROGENASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| CN-1186021-C | Antimicrobial compositions | HOFFMANN LA ROCHE (CH) | 2005-01-26 | — | — | CN | disclosed |
| CN-1216246-A | Antimicrobial composition | HOFFMANN LA ROCHE (CH) | 1999-05-12 | — | — | CN | disclosed |
| CN-1184815-A | Cephalosporin pyridinium derinvatives | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | CN | disclosed |
| CN-1184110-A | 1 -carba -(dethia) -cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1998-06-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221320-A1 | TREATMENT AND PREVENTION OF MUSCLE LOSS USING L-ORNITHINE IN COMBINATION WITH AT LEAST ONE OF PHENYLACETATE AND PHENYLBUTYRATE | OAT, CPT1B, OTC | TSHR 4066/4885ALDH1A1 543/4885L3MBTL1 61/4885 |
| US-10835506-B2 | Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate | OAT, CPT1B, OTC | TSHR 4066/4885ALDH1A1 543/4885L3MBTL1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.