Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861793 | 0.74 | KMT2A (1.00) | KMT2AMEN1POLBRECQLCTDSP1 | |
| SCHEMBL10441485 | 0.72 | HPGDS (0.58) | KMT2AMEN1POLBRAB9ANPC1 | |
| SCHEMBL27921277 | 0.72 | CES2 (0.55) | KMT2AMEN1POLBTDP1RAB9A | |
| SCHEMBL27921510 | 0.71 | CES2 (0.50) | KMT2AMEN1POLBRAB9ANPC1 | |
| SCHEMBL28845197 | 0.70 | CES2 (0.64) | KMT2AMEN1POLBTDP1RAB9A | |
| SCHEMBL12136717 | 0.70 | KMT2A (1.00) | KMT2AMEN1POLBRECQLCTDSP1 | |
| SCHEMBL27610864 | 0.69 | CES2 (0.61) | KMT2AMEN1POLBTDP1RAB9A | |
| SCHEMBL6653282 | 0.69 | F2 (0.49) | KMT2AMEN1POLBTDP1RAB9A | |
| SCHEMBL8457507 | 0.68 | GSK3B (0.56) | KMT2AMEN1POLBRAB9ANPC1 | |
| Potassium Ion SCHEMBL10701746 | 0.68 | CES2 (0.50) | KMT2AMEN1POLBTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188536-A1 | Modulation of pathogenicity | QUONOVA, LLC | 2008-08-07 | — | — | US | disclosed |
| US-20080188491-A1 | Modulation of pathogenicity | QUONOVA, LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188491-A1 | Modulation of pathogenicity | NR4A1, MSR1, NR4A2 | KMT2A 3525/4885MEN1 2823/4885POLB 3265/4885 |
| US-20080188536-A1 | Modulation of pathogenicity | NR4A1, NR4A2, NR4A3 | KMT2A 3588/4885MEN1 2784/4885POLB 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.