Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499158 | 0.77 | F2 (0.55) | F2ALDH1A1HPGDMAPTGAA | |
| SCHEMBL10441485 | 0.76 | HPGDS (0.58) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL6201640 | 0.75 | CES2 (0.47) | ALDH1A1HPGDMAPTGAACES2 | |
| SCHEMBL27921277 | 0.75 | CES2 (0.55) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL8457507 | 0.74 | GSK3B (0.56) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL27921510 | 0.74 | CES2 (0.50) | F2ALDH1A1HPGDMAPTCES2 | |
| SCHEMBL1865773 | 0.74 | RAB9A (0.62) | ALDH1A1HPGDMAPTGAATSHR | |
| SCHEMBL15988680 | 0.74 | HPGD (0.77) | ALDH1A1HPGDMAPTGAATSHR | |
| SCHEMBL28845197 | 0.74 | CES2 (0.64) | ALDH1A1HPGDMAPTGAACES2 | |
| SCHEMBL6672460 | 0.73 | CES2 (0.41) | ALDH1A1HPGDMAPTGAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478364-A2 | SELECTIVE ANTIBACTERIAL AGENTS | 4SC AG (DE) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003039549-A2 | SELECTIVE ANTIBACTERIAL AGENTS | 4SC AG (DE) | 2003-05-15 | — | — | WO | disclosed |