Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | C1R | P00736 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133931 | 0.74 | TDP1 (0.43) | TDP1ERN1MCL1ALDH1A1 | |
| SCHEMBL1053001 | 0.73 | TDP1 (0.50) | TDP1ERN1MEN1KMT2ALMNA | |
| SCHEMBL24028007 | 0.72 | ALDH1A1 (0.39) | TDP1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL24500913 | 0.72 | LMNA (0.52) | TDP1ERN1MCL1MEN1KMT2A | |
| SCHEMBL4844978 | 0.70 | ERN1 (0.46) | TDP1ERN1MEN1KMT2ALMNA | |
| SCHEMBL27196550 | 0.70 | ERN1 (0.37) | TDP1ERN1 | |
| SCHEMBL6187165 | 0.69 | TDP1 (0.46) | TDP1ERN1MEN1KMT2ALMNA | |
| SCHEMBL11387443 | 0.69 | MEN1 (0.46) | TDP1MCL1MEN1KMT2ALMNA | |
| SCHEMBL30525125 | 0.68 | TDP1 (0.33) | TDP1ERN1ALDH1A1 | |
| SCHEMBL29055095 | 0.68 | TDP1 (0.33) | TDP1ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881990-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | Boehringer Ingelheim International GmbH (DE) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006120208-A1 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES AND INTERMEDIATES THEREIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |