Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPM1A | P35813 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965276 | 0.94 | HDAC1 (0.36) | HDAC1HDAC2FFAR4FFAR1ESR1 | |
| SCHEMBL4965284 | 0.86 | PTGDR2 (0.34) | PPM1APTGDR2LTB4RFFAR4ESR1 | |
| SCHEMBL4965912 | 0.80 | FFAR4 (0.32) | FFAR4ESR1ESR2 | |
| SCHEMBL4965002 | 0.77 | ESR1 (0.50) | ESR1ESR2 | |
| SCHEMBL4965710 | 0.72 | ESR1 (0.55) | HDAC1HDAC2ESR1ESR2 | |
| SCHEMBL4965974 | 0.64 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL5851970 | 0.62 | ESR1 (0.61) | ESR1 | |
| SCHEMBL5138107 | 0.62 | CYP19A1 (0.54) | ESR1ESR2MAPT | |
| SCHEMBL15892136 | 0.57 | LTA4H (0.54) | MAPT | |
| SCHEMBL11614467 | 0.57 | MAPT (0.49) | PPARAMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641774-B1 | PENTAFLUOROALKANESULFINYL NAPHTHALENES AND RELATED ESTROGEN RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-09-03 | — | — | EP | claimed |
| US-20070054956-A1 | Pentalfluoroalkanesulfinyl naphthalenes and related estrogen receptor modulators | ELI LILLY AND COMPANY | 2007-03-08 | — | — | US | claimed |
| EP-1641774-A1 | PENTAFLUOROALKANESULFINYL NAPHTHALENES AND RELATED ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-04-05 | — | — | EP | claimed |
| WO-2005000834-A1 | PENTAFLUOROALKANESULFINYL NAPHTHALENES AND RELATED ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-01-06 | — | — | WO | claimed |
| US-7462647-B2 | Pentalfluoroalkanesulfinyl naphthalenes and related estrogen receptor modulators | ELI LILLY AND COMPANY (US) | 2008-12-09 | — | — | US | disclosed |
| EP-1641774-B1 | PENTAFLUOROALKANESULFINYL NAPHTHALENES AND RELATED ESTROGEN RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20070054956-A1 | Pentalfluoroalkanesulfinyl naphthalenes and related estrogen receptor modulators | ELI LILLY AND COMPANY | 2007-03-08 | — | — | US | disclosed |
| EP-1641774-A1 | PENTAFLUOROALKANESULFINYL NAPHTHALENES AND RELATED ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000834-A1 | PENTAFLUOROALKANESULFINYL NAPHTHALENES AND RELATED ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054956-A1 | Pentalfluoroalkanesulfinyl naphthalenes and related estrogen receptor modulators | ESR2, ESR1, GPER1 | HDAC1 2510/4885HDAC2 2386/4885PPARG 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.