Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 6/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26659934 | 0.83 | FYN (0.56) | NAAASLC13A5GRM2HTR7XDH | |
| SCHEMBL11673547 | 0.83 | NAAA (0.50) | NAAASLC13A5GRM2HTR7XDH | |
| SCHEMBL2006742 | 0.81 | HTR7 (0.51) | NAAASLC13A5GRM2HTR7XDH | |
| SCHEMBL2934073 | 0.81 | HTR7 (0.72) | HTR7PTPRCPTPN1KCNH2HTR1A | |
| SCHEMBL7221234 | 0.80 | HTR7 (0.57) | HTR7APPHTR1AHTR2CHTR2B | |
| SCHEMBL10892045 | 0.80 | ALDH1A1 (0.57) | APP | |
| SCHEMBL6950322 | 0.79 | KDM4E (0.46) | SLC13A5PPARGPPARAMMEMMEL1 | |
| SCHEMBL25146394 | 0.79 | S1PR1 (0.64) | NAAASLC13A5GRM2HTR7XDH | |
| SCHEMBL7229895 | 0.79 | CYP1A1 (0.46) | HTR7HTR2CPGR | |
| SCHEMBL19043338 | 0.79 | SLC13A5 (0.49) | NAAASLC13A5GRM2HTR7XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101090977-B | Tripeptide and tetrapeptide thioethers | TELIK INC | 2013-04-10 | — | — | CN | disclosed |
| US-20090318521-A1 | Synthesis of 4-Bromomethyl-2'-Formylbiphenyl and 4-Bromomethyl-2'-Hydroxymethylbiphenyl and Its Use in Preparation of Giotensin II Antagonists | LEK PHARMACEUTICALS D.D. (SI) | 2009-12-24 | — | — | US | disclosed |
| EP-1833842-B1 | TRIPEPTIDE AND TETRAPEPTIDE SULFONES | TELIK INC (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1833978-B1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | TELIK INC (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1833842-A1 | TRIPEPTIDE AND TETRAPEPTIDE SULFONES | TELIK, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-1833978-A1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | TELIK, INC. (US) | 2007-09-19 | — | — | EP | disclosed |
| US-7192918-B2 | Tripeptide and tetrapeptide sulfones | TELIK, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| WO-2006074409-A9 | TRIPEPTIDE AND TETRAPEPTIDE SULFONES | TELIK INC (US) | 2006-12-14 | — | — | WO | disclosed |
| US-7129215-B2 | Tripeptide and tetrapeptide thioethers | TELIK, INC. (US) | 2006-10-31 | — | — | US | disclosed |
| WO-2006103068-A1 | A SYNTHESIS OF 4-BROMOMETHYL-2'-FORMYLBIPHENYL AND 4-BROMOMETHYL-2'- HYDROXYMETHYLBIPHENYL AND ITS USE IN PREPARATION OF ANGIOTENSIN II ANTAGONISTS | LEK PHARMACEUTICALS D.D. (SI) | 2006-10-05 | — | — | WO | disclosed |
| US-20060160749-A1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | TELIK, INC. | 2006-07-20 | — | — | US | disclosed |
| WO-2006074249-A1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | TELIK, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| WO-2006074409-A1 | TRIPEPTIDE AND TETRAPEPTIDE SULFONES | TELIK, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060148719-A1 | Tripeptide and tetrapeptide sulfones | TELIK, INC. | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160749-A1 | TRIPEPTIDE AND TETRAPEPTIDE THIOETHERS | MCL1, THPO, MYADM | NAAA 2846/4885SLC13A5 3447/4885GRM2 2649/4885 |
| US-20060148719-A1 | Tripeptide and tetrapeptide sulfones | MCL1, MYD88, MYADM | NAAA 1759/4885SLC13A5 3068/4885GRM2 2647/4885 |
| US-20090318521-A1 | Synthesis of 4-Bromomethyl-2'-Formylbiphenyl and 4-Bromomethyl-2'-Hydroxymethylbiphenyl and Its Use in Preparation of Giotensin II Antagonists | GRK4, GRK2, GRK5 | NAAA 1205/4885SLC13A5 4160/4885GRM2 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.