SCHEMBL496710

SCHEMBL496710

Oc1ccc(-c2cscn2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
MKNK1 Q9BUB5 1/20 0.47
MKNK2 Q9HBH9 1/20 0.47
ESR2 Q92731 3/20 0.46
ESR1 P03372 2/20 0.46
MAPT P10636 5/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
POLB P06746 2/20 0.45
CYP19A1 P11511 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
CHEK2 O96017 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
USP2 O75604 3/20 0.41
LMNA P02545 2/20 0.41
GAA P10253 2/20 0.41
ALOX15 P16050 2/20 0.41
TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512842 0.80 RAB9A (0.47) LTA4HMAPTALDH1A1MEN1KMT2A
SCHEMBL18648678 0.79 POLB (0.51) ESR2MAPTALDH1A1HPGDHSD17B10
SCHEMBL14754324 0.78 RAB9A (0.47) ALDH1A1MEN1KMT2ACHEK2PARP1
SCHEMBL31126424 0.78 METAP2 (0.39) ESR1ALDH1A1CHEK2SMN1; SMN2TSHR
SCHEMBL1353491 0.78 METAP2 (0.46) MAPTALDH1A1HPGDHSD17B10MEN1
SCHEMBL10284703 0.78 KMT2A (0.48) LTA4HMAPTALDH1A1POLBMEN1
SCHEMBL679357 0.78 METAP2 (0.46) LTA4HMAPTALDH1A1HSD17B10CYP19A1
SCHEMBL1921559 0.78 CA2 (0.42) ESR1CHEK2SMN1; SMN2TSHRTDP1
SCHEMBL533611 0.78 FYN (0.45) MKNK1MKNK2ESR1CHEK2PARP1
SCHEMBL15384267 0.78 CHEK2 (0.48) ESR1HSD17B10CYP19A1CHEK2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384271-B1 Method for enhancement of chemiluminescence WAKO PURE CHEM IND LTD (JP) 1996-05-08 EP claimed
US-5106732-A Using oxazole or thiazole derivative TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-04-21 US claimed
EP-0384271-A2 Method for enhancement of chemiluminescence WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-08-29 EP claimed
JP-2291299-A None JP disclosed
EP-4325210-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE FUJIFILM Corporation (JP) 2024-02-21 EP disclosed
US-20240043742-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
US-11597702-B2 Substituted pyrazoles FFA4/GPR120 receptor agonists GOLGI NEUROSCIENCES S.R.L. (IT) 2023-03-07 US disclosed
WO-2022220288-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE 富士フイルム株式会社 2022-10-20 WO disclosed
CN-109503686-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2022-03-11 CN disclosed
EP-3366750-B1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2021-07-21 EP disclosed
CN-108546277-B Novel nucleoside phosphoramidate compounds and uses thereof 南京圣和药业股份有限公司 2021-05-07 CN disclosed
WO-1991013357-A1 IMPROVED IMMUNOASSAY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-05 WO disclosed
JP-H02291299-A METHOD FOR ENHANCING CHEMILUMINESCENCE TAKEDA CHEM IND LTD 1990-12-03 JP disclosed
EP-0384271-A2 Method for enhancement of chemiluminescence WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-08-29 EP disclosed
EP-0132165-A1 Adsorbable alkynyl substituted heterocyclic quaternary ammonium salts and applications thereof to silver halide photography EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-01-23 EP disclosed
US-4471044-A Silver halide emulsions and photographic elements containing adsorbable alkynyl substituted heterocyclic quaternary ammonium salts EASTMAN KODAK COMPANY (US) 1984-09-11 US disclosed
US-4179296-A CONTAINING A BENZIMIDAZOLOCARBOCYANINE DYE AND AT LEAST ONE OTHER CYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1979-12-18 US disclosed
US-4115122-A Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent FUJI PHOTO FILM CO., LTD. (JP) 1978-09-19 US disclosed
US-4094683-A HETEROCYCLIC QUATERNARY AMMONIUM COMPOUND AS FOGGING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1978-06-13 US disclosed
US-4053318-A SENSITIZING MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11597702-B2 Substituted pyrazoles FFA4/GPR120 receptor agonists FFAR4, FFAR3, FFAR1 LTA4H 464/4885MKNK1 2947/4885MKNK2 2314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.