Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515628 | 0.82 | RPS6KB2 (0.45) | L3MBTL1ALDH1A1CES2CES1GSK3B | |
| SCHEMBL5320621 | 0.80 | RPS6KB2 (0.51) | L3MBTL1ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL2615871 | 0.80 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1CES2CES1GSK3B | |
| SCHEMBL10639931 | 0.77 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1GSK3BLMNARXFP1 | |
| SCHEMBL27748238 | 0.77 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1CES2CES1GSK3B | |
| SCHEMBL1414863 | 0.76 | KDM4E (0.45) | L3MBTL1ALDH1A1CES2CES1GSK3B | |
| SCHEMBL9685034 | 0.76 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1DAOLMNARXFP1 | |
| SCHEMBL14741248 | 0.74 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1LMNARXFP1PRNP | |
| SCHEMBL7474007 | 0.74 | HPGD (0.58) | L3MBTL1ALDH1A1LMNARXFP1PRNP | |
| SCHEMBL482444 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750505-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033240-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| EP-1966194-A2 | SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007061948-A2 | SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-05-31 | — | — | WO | disclosed |