Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331378 | 0.81 | HPGD (0.50) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL4967153 | 0.80 | L3MBTL1 (0.47) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL9699843 | 0.79 | GSK3B (0.46) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL11104922 | 0.79 | HDAC1 (0.44) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL11104919 | 0.79 | CES2 (0.48) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL1598343 | 0.79 | HDAC1 (0.44) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL31298142 | 0.78 | L3MBTL1 (0.43) | L3MBTL1HDAC1HDAC6CES2CES1 | |
| SCHEMBL9374537 | 0.77 | PRMT6 (0.47) | L3MBTL1DAOKDM4ETDP1KMT2A | |
| SCHEMBL5582083 | 0.76 | SMN1; SMN2 (0.50) | L3MBTL1HDAC1HDAC6KMT2AMEN1 | |
| SCHEMBL4239545 | 0.75 | ALDH1A1 (0.50) | GSK3BDAOKDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |
| US-9334304-B2 | Self-assembling peptides bearing organic electronic functionality and applications employing the same | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-05-10 | — | — | US | disclosed |
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-31 | — | — | US | disclosed |
| US-20120101022-A1 | SELF-ASSEMBLING PEPTIDES BEARING ORGANIC ELECTRONIC FUNCTIONALITY AND APPLICATIONS EMPLOYING THE SAME | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213538-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | L3MBTL1 2087/4885HDAC1 2445/4885HDAC6 2729/4885 |
| US-20120101022-A1 | SELF-ASSEMBLING PEPTIDES BEARING ORGANIC ELECTRONIC FUNCTIONALITY AND APPLICATIONS EMPLOYING THE SAME | APP, IAPP, DNPEP | L3MBTL1 832/4885HDAC1 4804/4885HDAC6 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.