SCHEMBL496722

SCHEMBL496722

CCOc1c(C(C)(C)C)cc(CP(=O)(O)O)cc1C(C)(C)C.CCOc1c(C(C)(C)C)cc(CP(=O)(O)O)cc1C(C)(C)C.[Ni]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 2/20 0.43
PGK2 P07205 2/20 0.43
HMGCR P04035 3/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
BLM P54132 1/20 0.37
ATM Q13315 1/20 0.37
HIF1A Q16665 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PTPRB P23467 2/20 0.37
THRB P10828 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7192142 0.98 PGK1 (0.44) PGK1PGK2HMGCRMEN1KMT2A
Calcium SCHEMBL6227678 0.97 PGK1 (0.43) PGK1PGK2HMGCRMEN1KMT2A
SCHEMBL1509708 0.90 HMGCR (0.42) PGK1PGK2HMGCRMEN1KMT2A
SCHEMBL10825681 0.87 ENPP2 (0.41) PGK1PGK2HMGCRMEN1KMT2A
SCHEMBL11080455 0.86 HMGCR (0.46) PGK1PGK2HMGCRMEN1KMT2A
SCHEMBL10830497 0.85 HMGCR (0.42) PGK1PGK2HMGCRMEN1KMT2A
SCHEMBL11581509 0.84 ENPP2 (0.46) THRBTHRAENPP2
SCHEMBL11139109 0.84 ENPP2 (0.41) PGK1PGK2HMGCRMEN1KMT2A
Calcium SCHEMBL10683245 0.84 ENPP2 (0.41) PGK1PGK2HMGCRMEN1KMT2A
SCHEMBL4276263 0.83 PGK1 (0.44) PGK1PGK2HMGCRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187082-B1 COMPOSITION COMPRISED OF THIOUREA AND INK CARBAMATE, EACH WITH SPECIFIED MELTING POINT AND ACOUSTIC-LOSS VALUE, LIGHTFASTNESS COMPONENT, LIGHTFAST ANTIOXIDANT, COLORANT XEROX CORPORATION 2001-02-13 US claimed
US-6132499-A Inks XEROX CORPORATION (US) 2000-10-17 US claimed
US-6045607-A FIRST AND SECOND SOLID CARBAMATES WITH A DISSIMILAR MELTING POINTS; LIGHTFASTNESS COMPONENT; A LIGHTFASTNESS ANTIOXIDANTS, AND A COLORANT; USEFUL FOR ACOUSTIC INK PRINTING XEROX CORPORATION (US) 2000-04-04 US claimed
EP-0854167-A2 Silicone molding compositions having extended useful life GENERAL ELECTRIC COMPANY (US) 1998-07-22 EP claimed
US-5310771-A Ultraviolet resistance, hindered amines, metal phosphonates, triazines PHILLIPS PETROLEUM COMPANY (US) 1994-05-10 US claimed
EP-0567117-A1 Polyolefin stabilization PHILLIPS PETROLEUM COMPANY (US) 1993-10-27 EP claimed
EP-0218768-A2 Compositions containing antimicrobial agents in combination with stabilizers MORTON THIOKOL, INC. (US) 1987-04-22 EP claimed
US-4624679-A Compositions containing antimicorbial agents in combination with stabilizers MORTON THIOKOL, INC. (US) 1986-11-25 US claimed
EP-0042629-B1 ACTIVATION OF BLOWING AGENTS UNIROYAL, INC. (US) 1984-07-25 EP claimed
US-4076689-A ZINC OXIDE, A ZINC DIHYDROCARBYLDITHIOCARBAMATE,A NICKEL BIS(HYDROXYPHENYL-ALKYLPHOSPHONATE) PHILLIPS PETROLEUM COMPANY (US) 1978-02-28 US claimed
US-8106135-B2 Polyethersulfone compositions with high heat and good impact resistance SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-31 US disclosed
US-20070117962-A1 High heat polyethersulfone compositions GENERAL ELECTRIC COMPANY (US) 2007-05-24 US disclosed
US-20070049724-A1 POLYETHERSULFONE COMPOSITIONS WITH HIGH HEAT AND GOOD IMPACT RESISTANCE GENERAL ELECTRIC COMPANY (US) 2007-03-01 US disclosed
WO-2002006392-A1 STABILIZER COMPOSITIONS COMPRSING A MONOMERIC DIHYDROPYRIDINE DERIVATIVE AND THEIR USE AKZO NOBEL N.V. (US) 2002-01-24 WO disclosed
US-20010018488-A1 Silicone molding compositions having extended useful life GENERAL ELECTRIC CO. 2001-08-30 US disclosed
EP-0027926-A1 Degradation resistant polyolefin articles and process for making same PHILLIPS PETROLEUM COMPANY (US) 1981-05-06 EP disclosed
US-4166814-A LIGHT STABILIZATION OF POLYMERS CIBA-GEIGY CORPORATION (US) 1979-09-04 US disclosed
US-4113914-A BLOCK POLYMER OF SYTRENE AND BUTADIENE OR ISOPRENE PHILLIPS PETROLEUM COMPANY (US) 1978-09-12 US disclosed
US-4076689-A ZINC OXIDE, A ZINC DIHYDROCARBYLDITHIOCARBAMATE,A NICKEL BIS(HYDROXYPHENYL-ALKYLPHOSPHONATE) PHILLIPS PETROLEUM COMPANY (US) 1978-02-28 US disclosed
US-3991130-A Organo-nickel salts as adhesion promotors for vulcanizable elastomers to metals CIBA-GEIGY CORPORATION (US) 1976-11-09 US disclosed