Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.44 |
| ▸ | PGK2 | P07205 | 2/20 | 0.44 |
| ▸ | HMGCR | P04035 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496722 | 0.98 | PGK1 (0.43) | PGK1PGK2HMGCRMEN1KMT2A | |
| Calcium SCHEMBL6227678 | 0.98 | PGK1 (0.43) | PGK1PGK2HMGCRMEN1KMT2A | |
| SCHEMBL1509708 | 0.92 | HMGCR (0.42) | PGK1PGK2HMGCRMEN1KMT2A | |
| SCHEMBL11080455 | 0.88 | HMGCR (0.46) | PGK1PGK2HMGCRMEN1KMT2A | |
| SCHEMBL10830497 | 0.86 | HMGCR (0.42) | PGK1PGK2HMGCRMEN1KMT2A | |
| SCHEMBL10825681 | 0.85 | ENPP2 (0.41) | PGK1PGK2HMGCRMEN1KMT2A | |
| SCHEMBL11139109 | 0.85 | ENPP2 (0.41) | PGK1PGK2HMGCRMEN1KMT2A | |
| Calcium SCHEMBL10683245 | 0.85 | ENPP2 (0.41) | PGK1PGK2HMGCRMEN1KMT2A | |
| Calcium SCHEMBL10688521 | 0.83 | HMGCR (0.39) | HMGCRMEN1KMT2AGAAUSP2 | |
| Calcium SCHEMBL10682160 | 0.83 | ENPP2 (0.46) | THRBTHRAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | claimed |
| EP-0042629-B1 | ACTIVATION OF BLOWING AGENTS | UNIROYAL, INC. (US) | 1984-07-25 | — | — | EP | claimed |
| EP-0042629-A1 | Activation of blowing agents | UNIROYAL, INC. (US) | 1981-12-30 | — | — | EP | claimed |
| EP-0734414-B2 | STABILISED VINYL CHLORIDE COMPOSITION | AKCROS CHEM (GB) | 2003-10-22 | — | — | EP | disclosed |
| EP-0734414-B1 | STABILISED VINYL CHLORIDE COMPOSITION | AKCROS CHEM (GB) | 1999-03-03 | — | — | EP | disclosed |
| US-5585042-A | REVERSIBLE CHANGE IN COLOR WHEN EXPOSURED TO ULTRAVIOLET RADIATION | TRANSITIONS OPTICAL, INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0734414-A1 | STABILISED VINYL CHLORIDE COMPOSITION | AKCROS CHEMICALS (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016739-A1 | STABILISED VINYL CHLORIDE COMPOSITION | AKCROS CHEMICALS (GB) | 1995-06-22 | — | — | WO | disclosed |
| US-5395567-A | For use in ophthalmic lenses; efficient reversible color change on exposure to uv rad | PPG INDUSTRIES, INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-4440672-A | SPIRO(INDOLINE-2,3'-(3'H)-NAPHTN(1,2-B)(1,4) OXAZINES), ULTRAVIOLET STABILIZER | AMERICAN OPTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| US-4259453-A | HYDRAZODICARBOXYLATE BLOWING AGENT FOR EXPANDING POLYMERIC MATERIAL | UNIROYAL, INC. (US) | 1981-03-31 | — | — | US | disclosed |
| US-4135014-A | GLASS BOTTLE COATING COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4104256-A | ALKYL PHOSPHONIC ACIDS OR MONOALKYLESTER OF AN ALKYL PHOSPHONIC ACID | UNION CARBIDE CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |