Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252300 | 0.80 | SNCA (0.38) | SNCANPC1RAB9ATAAR1 | |
| SCHEMBL1250647 | 0.79 | HTR2A (0.39) | ALDH1A1 | |
| SCHEMBL4968853 | 0.78 | LMNA (0.40) | SNCASMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL4969708 | 0.76 | MAPT (0.44) | SMN1; SMN2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL4965624 | 0.75 | CSNK2A1 (0.33) | SNCA | |
| SCHEMBL4966913 | 0.74 | NPC1 (0.36) | SMN1; SMN2NPC1MAPTRAB9ATAAR1 | |
| SCHEMBL1252956 | 0.73 | SLC5A2 (0.39) | TAAR1ALDH1A1 | |
| SCHEMBL4966210 | 0.72 | KMT2A (0.41) | MAPTPOLB | |
| SCHEMBL2240779 | 0.72 | SNCA (0.36) | SNCASMN1; SMN2MAPTRAB9ATAAR1 | |
| SCHEMBL24199822 | 0.72 | SNCA (0.42) | SNCANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |