Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TST | Q16762 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536586 | 0.93 | ESR1 (0.59) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL2323477 | 0.91 | ESR1 (0.63) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL504392 | 0.91 | ESR1 (0.63) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL2686704 | 0.91 | ESR1 (0.63) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL503866 | 0.84 | ESR1 (0.68) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL1171041 | 0.84 | ESR1 (0.77) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL449737 | 0.84 | ESR1 (0.77) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL245139 | 0.84 | ESR1 (0.77) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL1447579 | 0.81 | ESR1 (0.77) | ESR1ESR2ADRA2ASLC6A2ADORA3 | |
| SCHEMBL9165397 | 0.81 | ESR1 (0.77) | ESR1ESR2ADRA2ASLC6A2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364948-A | Anticancer, anticholesterol, fungicide | MERCK & CO., INC. (US) | 1994-11-15 | — | — | US | claimed |
| WO-1994018157-A1 | BIOLOGICALLY ACTIVE COMPOUNDS ISOLATED FROM AEROBIC FERMENTATION OF $i(TRICHODERMA VIRIDE) | MERCK & CO., INC. (US) | 1994-08-18 | — | — | WO | claimed |
| CN-115698110-A | Curable resin composition, molded article, and method for producing same | 三菱瓦斯化学株式会社 | 2023-02-03 | — | — | CN | disclosed |
| CN-109790292-B | Process for preparing polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2022-05-31 | — | — | CN | disclosed |
| WO-2021241378-A1 | CURABLE RESIN COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING SAME | 三菱瓦斯化学株式会社 | 2021-12-02 | — | — | WO | disclosed |
| CN-106154792-B | Image forming apparatus with a toner supply device | 东芝泰格有限公司 | 2020-03-03 | — | — | CN | disclosed |
| CN-107635787-A | Laser-markable composition, material and file | 爱克发-格法特公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107636085-A | Water-based jet ink | 爱克发-格法特公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107635786-A | Can laser labelling material and file | 爱克发-格法特公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107592840-A | LASER MARKABLE COMPOSITIONS, ARTICLES AND DOCUMENTS | 爱克发-格法特公司 | 2018-01-16 | — | — | CN | disclosed |
| CN-104334535-B | Dendrimer-like aminoamides with sodium channel blocking activity for the treatment of dry eye and other mucosal diseases | 帕里昂科学公司 | 2016-10-05 | — | — | CN | disclosed |
| US-5393774-A | Antispasmodic agents | PIEPER HELMUT (DE) | 1995-02-28 | — | — | US | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |
| CN-1068333-A | Has hydrazine analog derivative of pharmacologically active and preparation method thereof | CIBA GEIGY AG (CH) | 1993-01-27 | — | — | CN | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| US-4988681-A | Dipeptidase inhibitore; reducing renal toxicity; prevention deactivation of (carba)penem antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0347840-A2 | Phosphinic acid derivates | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0137722-A2 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1985-04-17 | — | — | EP | disclosed |
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |