SCHEMBL2686704

SCHEMBL2686704

[CH2]CCCCCCCCc1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.63
ADRA2A P08913 3/20 0.63
SLC6A2 P23975 3/20 0.63
ACHE P22303 3/20 0.63
ADORA3 P0DMS8 2/20 0.63
TACR2 P21452 2/20 0.63
SLC6A4 P31645 2/20 0.63
SLC6A3 Q01959 2/20 0.63
KDM4E B2RXH2 2/20 0.63
ALDH1A1 P00352 2/20 0.63
LMNA P02545 1/20 0.63
SHBG P04278 1/20 0.63
TP53 P04637 1/20 0.63
CYP3A4 P08684 1/20 0.63
HSPD1 P10809 1/20 0.63
ADRB3 P13945 1/20 0.63
HTR2C P28335 1/20 0.63
HSPE1 P61604 1/20 0.63
HIF1A Q16665 1/20 0.63
TST Q16762 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504392 1.00 ESR1 (0.63) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL2323477 1.00 ESR1 (0.63) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL5536586 0.98 ESR1 (0.59) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL4967337 0.91 ESR1 (0.62) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL8398450 0.88 ESR1 (0.77) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL9165397 0.88 ESR1 (0.77) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL1447579 0.88 ESR1 (0.77) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL2777921 0.88 ESR1 (0.77) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL9166790 0.88 ESR1 (0.77) ESR1ADRA2ASLC6A2ACHEADORA3
SCHEMBL7784766 0.88 ESR1 (0.77) ESR1ADRA2ASLC6A2ACHEADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
CN-102439089-B Curable resin composition ADEKA CORP 2015-05-06 CN disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
EP-2586827-A1 CURABLE RESIN COMPOSITION Adeka Corporation (JP) 2013-05-01 EP disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
CN-102439089-A Curable resin composition ADEKA CORP 2012-05-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 ESR1 632/4885ADRA2A 2691/4885SLC6A2 4298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.