Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28130066 | 0.98 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2907991 | 0.85 | PNMT (0.54) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL10398011 | 0.84 | TSHR (0.42) | ALDH1A1KDM4ESMN1; SMN2KMT2ALMNA | |
| SCHEMBL4013559 | 0.83 | PNMT (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4013563 | 0.83 | PNMT (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1194386 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11757162 | 0.81 | TSHR (0.40) | ALDH1A1KDM4ESMN1; SMN2KMT2ALMNA | |
| SCHEMBL5963 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3028541 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL11831456 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492390-B2 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2013-07-23 | — | — | US | claimed |
| EP-2578577-A1 | Sulfonyl esters of tetrahydrocannabinol and derivatives thereof | Albany Molecular Research, Inc. (US) | 2013-04-10 | — | — | EP | claimed |
| US-8084458-B2 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2011-12-27 | — | — | US | claimed |
| US-20100216983-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA A/S, a Denmark corporation | 2010-08-26 | — | — | US | claimed |
| US-7674922-B2 | Process for production of delta-9-tetrahydrocannabinol | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-03-09 | — | — | US | claimed |
| US-7569575-B2 | Formed via intermediates which are reactive with nucleophiles | SANTARIS PHARMA A/S (DK) | 2009-08-04 | — | — | US | claimed |
| EP-1928853-A2 | PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL | AMR Technology, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| EP-1501848-B1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA AS (DK) | 2007-08-08 | — | — | EP | claimed |
| US-20070093665-A1 | Process for production of delta-9- tetrahydrocannabinol | AMR TECHNOLOGY, INC. (US) | 2007-04-26 | — | — | US | claimed |
| WO-2007041167-A2 | PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL | AMR TECHNOLOGY, INC. (US) | 2007-04-12 | — | — | WO | claimed |
| EP-1163250-B1 | IMPROVED SYNTHESIS OF ¬2.2.1|BICYCLO NUCLEOSIDES | EXIQON AS (DK) | 2006-07-12 | — | — | EP | claimed |
| EP-1501848-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | Santaris Pharma A/S (DK) | 2005-02-02 | — | — | EP | claimed |
| US-20040014959-A1 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2004-01-22 | — | — | US | claimed |
| WO-2003095467-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA A/S (DK) | 2003-11-20 | — | — | WO | claimed |
| CN-109233322-B | Blue acid dye and preparation method thereof | 绍兴金美珂化工有限公司 | 2020-04-07 | — | — | CN | disclosed |
| US-9783534-B2 | Crystalline form of 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1, 3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenylmethanesulphonate | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-10-10 | — | — | US | disclosed |
| US-20160251344-A1 | Novel crystalline form of 2-piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenylmethanesulphonate | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-09-01 | — | — | US | disclosed |
| WO-1990002731-A1 | PROCESS FOR THE PREPARATION OF 4-SULFO-2-CHLOROBENZOIC ACID | INTEROX CHEMICALS LIMITED (GB) | 1990-03-22 | — | — | WO | disclosed |
| US-4415574-A | BACTERICIDES; MEDICINES; POTENTIATION OF SULFA DRUGS | S. A. PANMEDICA (FR) | 1983-11-15 | — | — | US | disclosed |
| US-4139530-A | CATIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216983-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | RNGTT, NSUN3, NSUN2 | ALDH1A1 1716/4885KDM4E 2204/4885MAPT 2218/4885 |
| US-20070093665-A1 | Process for production of delta-9- tetrahydrocannabinol | CNR2, CNR1, HRH4 | ALDH1A1 2849/4885KDM4E 2374/4885MAPT 2643/4885 |
| US-20040014959-A1 | Synthesis of locked nucleic acid derivatives | NSUN3, RNGTT, NSUN2 | ALDH1A1 1589/4885KDM4E 2081/4885MAPT 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.