Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9497174 | 1.00 | TSHR (0.40) | TSHRHPGDPTGER2GAATDP1 | |
| SCHEMBL2677059 | 0.99 | HPGD (0.41) | TSHRHPGDPTGER2GAATDP1 | |
| SCHEMBL2720980 | 0.99 | HPGD (0.41) | TSHRHPGDPTGER2GAATDP1 | |
| SCHEMBL11787951 | 0.99 | HPGD (0.41) | TSHRHPGDPTGER2GAATDP1 | |
| SCHEMBL4967427 | 0.99 | HPGD (0.41) | TSHRHPGDPTGER2GAATDP1 | |
| SCHEMBL9498988 | 0.85 | CYP4F2 (0.44) | TSHRGAATDP1EPHX2ALDH1A1 | |
| SCHEMBL10753712 | 0.85 | CYP4F2 (0.44) | TSHRGAATDP1EPHX2ALDH1A1 | |
| SCHEMBL11810537 | 0.85 | CYP4F2 (0.44) | TSHRGAATDP1EPHX2ALDH1A1 | |
| SCHEMBL11808317 | 0.85 | CYP4F2 (0.44) | TSHRGAATDP1EPHX2ALDH1A1 | |
| SCHEMBL9496265 | 0.85 | CYP4F2 (0.44) | TSHRGAATDP1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247620-B1 | PRODUCTION OF CYCLOPENTENONES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-4957867-A | Production of cyclopentenones by enzyme resolution | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0247620-A2 | Production of cyclopentenones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-02 | — | — | EP | disclosed |